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Progranulin in frontotemporal lobar degeneration and neuroinflammationbeta-Amyloid degradation and Alzheimer's diseaseImpaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic miceRibosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's diseaseHeterodimerization of Lrrk1-Lrrk2: Implications for LRRK2-associated Parkinson diseaseActin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistryBRI2 (ITM2b) inhibits Abeta deposition in vivoMutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal deathLRRK2 phosphorylates novel tau epitopes and promotes tauopathyUnconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALSGenetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's diseaseInvestigation of 15 of the top candidate genes for late-onset Alzheimer's diseaseCharacterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadicsExpanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALSA novel human disease with abnormal prion protein sensitive to proteaseArgyrophilic grains: a distinct disease or an additive pathology?Validation of the neuropathologic criteria of the third consortium for dementia with Lewy bodies for prospectively diagnosed casesThe neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer diseaseClinicopathologic assessment and imaging of tauopathies in neurodegenerative dementiasRarity of the Alzheimer disease-protective APP A673T variant in the United StatesMutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathologyDeposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB)Oxidized neprilysin in aging and Alzheimer's disease brainsComparison of kindreds with parkinsonism and alpha-synuclein genomic multiplicationsCHIP and Hsp70 regulate tau ubiquitination, degradation and aggregationTranslation initiator EIF4G1 mutations in familial Parkinson diseaseMutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17Association and heterogeneity at the GAPDH locus in Alzheimer's diseaseSingle-dose intracerebroventricular administration of galactocerebrosidase improves survival in a mouse model of globoid cell leukodystrophyNovel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosisA novel calcium-binding protein is associated with tau proteins in tauopathyCommon variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseDiagnosis and management of dementia with Lewy bodies: third report of the DLB ConsortiumCommon variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's diseaseNovel A18T and pA29S substitutions in α-synuclein may be associated with sporadic Parkinson's disease.Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis.
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Dennis Dickson
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Dennis W Dickson
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Dennis W. Dickson
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