Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide. - Test2 - elhamkhani - TriplyDB

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

http://www.wikidata.org/entity/Q30582056

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Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Mitohormesis SIRTain regulators of premature senescence and accelerated aging Mitochondrial proteostasis in the control of aging and longevity Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae.Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds Deep Proteome Analysis Identifies Age-Related Processes in C. elegans ROS function in redox signaling and oxidative stress Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Nicotinamide metabolism regulates glioblastoma stem cell maintenance.It takes two to tango: NAD+ and sirtuins in aging/longevity control NAD+ and sirtuins in aging and disease.N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans.Effects of nutritional components on aging Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus Systemic regulation of mammalian ageing and longevity by brain sirtuins.Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.Knockout of silent information regulator 2 (SIRT2) preserves neurological function after experimental stroke in mice.Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD(+) homeostasis and contributes to longevity.Calorie restriction and sirtuins revisited SIRT1 and other sirtuins in metabolism.D-Glucosamine supplementation extends life span of nematodes and of ageing mice.The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling.SIRT1 metabolic actions: Integrating recent advances from mouse models.Senescence suppressors: their practical importance in replicative lifespan extension in stem cells.Lifespan-regulating genes in C. elegans.Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme.Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.Cellular lifespan and senescence: a complex balance between multiple cellular pathways.NAD and the aging process: Role in life, death and everything in between.Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models.Dietary restriction involves NAD⁺ -dependent mechanisms and a shift toward oxidative metabolism.Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

http://www.wikidata.org/entity/Q30582056

description

2013 nî lūn-bûn

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2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Nature Chemical Biology

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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

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Alexandra Segref

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Andreas F H Pfeiffer

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Haim Y Cohen

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Johannes Mansfeld

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Marco Groth

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Nathan L Price

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Sandra Weimer

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Stefan Schuster

http://www.w3.org/2001/XMLSchema#string

Steffen Priebe

http://www.w3.org/2001/XMLSchema#string

Yariv Kanfi

http://www.w3.org/2001/XMLSchema#string

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Sir2-independent life span extension by calorie restriction in yeast

Differential expression analysis for sequence count data

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Antioxidants prevent health-promoting effects of physical exercise in humans

TopHat: discovering splice junctions with RNA-Seq

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

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693-700

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10.1038/NCHEMBIO.1352

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11

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9

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Matthias Platzer

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Kathrin Schmeisser

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2013-09-29T00:00:00Z

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257205360

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24077178

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4076143

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