Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.
about
Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling.Structure of the RZZ complex and molecular basis of its interaction with Spindly.Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly.A Molecular View of Kinetochore Assembly and Function.Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability.Kinetochore assembly and function through the cell cycle.Playing polo during mitosis: PLK1 takes the lead.The RZZ complex requires the N-terminus of KNL1 to mediate optimal Mad1 kinetochore localization in human cells.Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.Evolutionary dynamics of the kinetochore network in eukaryotes as revealed by comparative genomics.Kinetochore Malfunction in Human Pathologies.Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling.Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation.A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.Bub1/BubR1: swiss army knives at kinetochores.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.The greatest kinetochore show on earth.The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling.Novel ESCRT functions at kinetochores.The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.MAD1: Kinetochore Receptors and Catalytic Mechanisms.Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymesSelf-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment
P2860
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P2860
Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@ast
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@en
type
label
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@ast
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@en
prefLabel
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@ast
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@en
P2860
P50
P356
P1476
Distinct domains in Bub1 local ...... es to regulate the checkpoint.
@en
P2093
Daniel G Hayward
P2860
P2888
P356
10.1038/NCOMMS8162
P407
P577
2015-06-02T00:00:00Z
P5875
P6179
1042620007