The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
about
Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisCharacterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCp55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinaseThe Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregationImpairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomasDifferential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointZwilch, a new component of the ZW10/ROD complex required for kinetochore functionsStructural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionSimian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signalingDynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Bub1 regulates chromosome segregation in a kinetochore-independent mannerCentromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossA microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingBuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignmentMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresCENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells.Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplicationUncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresLesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiaeCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexIdentification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulationBub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesisMammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpointsLinking kinetochore-microtubule binding to the spindle checkpointThe crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochoresCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2The Nup107-160 nucleoporin complex is required for correct bipolar spindle assemblyStructural analysis of Bub3 interactions in the mitotic spindle checkpointRapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cellsMicrotubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signalingSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activitySpindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochoresHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresCell division: control of the chromosomal passenger complex in time and spaceFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
P2860
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P248
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P2860
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@ast
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en-gb
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@nl
type
label
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@ast
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en-gb
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@nl
prefLabel
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@ast
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en-gb
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@nl
P2093
P2860
P3181
P356
P1476
The human homologue of Bub3 is ...... d3/Bub1-related protein kinase
@en
P2093
P2860
P3181
P356
10.1083/JCB.142.1.1
P407
P577
1998-07-13T00:00:00Z