Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling - Test2 - elhamkhani - TriplyDB

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

http://www.wikidata.org/entity/Q30844828

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Wnt signaling networks in autism spectrum disorder and intellectual disability Delineating the Common Biological Pathways Perturbed by ASD's Genetic Etiology: Lessons from Network-Based Studies Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry.Epigenetic Mistakes in Neurodevelopmental Disorders.Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development.Autism spectrum disorder: neuropathology and animal models.Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders.Toward a conceptual framework for early brain and behavior development in autism.Genomic Patterns of De Novo Mutation in Simplex Autism.Germline Chd8 haploinsufficiency alters brain development in mouse.The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function.Neural Progenitor Cell Polarity and Cortical Development.miR-124 promotes proliferation and differentiation of neuronal stem cells through inactivating Notch pathway.APC sets the Wnt tone necessary for cerebral cortical progenitor development.Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder.Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System.Multiple roles of Ulk4 in neurogenesis and brain function.Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.Enrichment of factors regulating canonical Wnt signaling among autism risk genes.ATP-Dependent Chromatin Remodeling During Cortical Neurogenesis.UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice.Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: opportunities for translation.The Wnt Signaling Pathway and Related Therapeutic Drugs in Autism Spectrum Disorder.Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster.Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair Social Stimulus Causes Aberrant Activation of the Medial Prefrontal Cortex in a Mouse Model With Autism-Like Behaviors Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

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Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

http://www.wikidata.org/entity/Q30844828

description

2016 nî lūn-bûn

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2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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type

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

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Nature Neuroscience

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Chd8 mediates cortical neuroge ...... f cell cycle and Wnt signaling

@en

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Anthony J Martorell

http://www.w3.org/2001/XMLSchema#string

Carol Y Liu

http://www.w3.org/2001/XMLSchema#string

Fan Gao

http://www.w3.org/2001/XMLSchema#string

L Ashley Watson

http://www.w3.org/2001/XMLSchema#string

Li-Huei Tsai

http://www.w3.org/2001/XMLSchema#string

Omer Durak

http://www.w3.org/2001/XMLSchema#string

Yea Jin Kaeser-Woo

http://www.w3.org/2001/XMLSchema#string

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Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway

Disruptive CHD8 mutations define a subtype of autism early in development

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

Early embryonic death in mice lacking the beta-catenin-binding protein Duplin

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome

The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene

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10.1038/NN.4400

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11

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19

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5386887

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