Disruptive CHD8 mutations define a subtype of autism early in development
about
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitorsGenome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial MorphologyThe Interaction between the Immune System and Epigenetics in the Etiology of Autism Spectrum DisordersFunction Over Form: Modeling Groups of Inherited Neurological Conditions in ZebrafishPrenatal Neurogenesis in Autism Spectrum DisordersA Short Review on the Current Understanding of Autism Spectrum DisordersMutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism EtiologyMoving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disordersBehavioral phenotypes of genetic mouse models of autism.Characterizing autism spectrum disorders by key biochemical pathways.Genes, circuits, and precision therapies for autism and related neurodevelopmental disordersFunctional Insights into Chromatin Remodelling from Studies on CHARGE SyndromeChromodomain helicase DNA-binding proteins in stem cells and human developmental diseasesThe study of psychiatric disease genes and drugs in zebrafishThe promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disordersTwo knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis.Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouseThe bowel and beyond: the enteric nervous system in neurological disordersAdvancing the understanding of autism disease mechanisms through geneticsWnt signaling networks in autism spectrum disorder and intellectual disabilityThe Chromatin Regulator CHD8 Is a Context-Dependent Mediator of Cell Survival in Murine Hematopoietic MalignanciesMutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone AcetylationDe Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive DysmorphismsMultisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11BDeveloping highER-throughput zebrafish screens for in-vivo CNS drug discovery.BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.Unsupervised data-driven stratification of mentalizing heterogeneity in autism.Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signalingExploring the heterogeneity of neural social indices for genetically distinct etiologies of autism.An ontology for Autism Spectrum Disorder (ASD) to infer ASD phenotypes from Autism Diagnostic Interview-Revised data.Toddlers later diagnosed with autism exhibit multiple structural abnormalities in temporal corpus callosum fibers.In pursuit of neurophenotypes: The consequences of having autism and a big brain.Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated childrenChd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal CircuitsUsing Animal Models to Study the Role of the Gut-Brain Axis in Autism.Examining the Causes of Autism.Bio-collections in autism research.The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.Recurrent de novo mutations implicate novel genes underlying simplex autism riskEpigenetic Developmental Disorders: CHARGE syndrome, a case study
P2860
Q24305288-3A32CA30-9795-46E0-9B10-47A5C3FDAC6AQ26714036-3E112A6B-1A7E-4556-99B4-6B4A72D385CFQ26741427-D7A6BEA2-2C87-4BDC-B81C-3AA55B760EC2Q26741616-3A010FFE-1E09-4895-971F-162BB457154FQ26750832-DAD338C8-C96F-42F0-A4FD-74DD2ACEC957Q26765918-B3CA47E4-C2CE-4AC2-BC39-7E779DC5F058Q26770773-0C9414B2-A5A8-488F-A030-CB5B258D3DDEQ26779153-94B556D8-7A3F-4E16-BED4-7AE0112C78B1Q26781456-66AFF212-1CC9-434B-AE4D-6677A23C8DCFQ26781645-41C3584F-AD09-4F1A-9D72-002ED2D0BB0DQ26782594-99F91DCF-5E16-4ED3-9A80-422442448AD7Q26786457-98192064-2AC6-4EFD-A4B6-2C0E2068DBB1Q26822979-2403EC87-DF38-46E8-A370-EB7453C8EE1DQ26824671-B185975D-3894-4F0E-92B5-E8C709D5ED7CQ27005952-EF0BC061-A9F9-49F0-BB84-9BE98D49EC5CQ27301001-B5E171D8-95DF-4EC8-9655-A8C364F05F3AQ27339100-50E74B5F-A620-447F-B273-C690DF78C1E2Q28069344-9A53FDA8-52AC-4AED-A4C2-5753B4CEC3C6Q28069757-EE0487AF-348C-40C8-A120-D46036EEB3A2Q28074740-1FDDA339-ABEB-4A35-A1DD-8C3D2EA70933Q28551057-BE57C88E-C184-48FE-A719-5E73089CEE03Q29144895-524950B6-BD79-481D-B6BB-758D7412D3F9Q29147465-23F8FFAC-3E55-45D5-B76A-083A6050A73FQ29147572-617BF0A0-9695-4FF0-B4F6-DD9B35B05C7AQ30620310-3CA97523-E04D-4CB9-9681-6C9353400EFCQ30657341-76AA8870-82DF-4FE1-8AFD-6B4300671E44Q30823455-06F92575-483D-4C8A-A187-4C3B35ECF4CCQ30844828-921FE985-EC29-4835-9220-6F9CE0166EB8Q30853711-7141AA89-00EC-44CF-A8A3-C61E72B6C915Q30979052-A7D3C4E9-BFC2-45B4-B53D-A1246A8B0B80Q31162231-375DF2C6-BF20-4581-BB4E-3FE9ECC19B96Q31166662-C9B565DA-ECC7-4E41-A8B9-601D775DA020Q33707712-A77F3CD2-8022-407B-8150-F567D312C953Q33756508-4EB68C40-55FF-43F2-97FB-EF6FAF02A9C8Q33845511-0A79096D-252C-4EE0-A273-B84A1F33F25DQ33882648-75FB6E2A-7EC6-42F8-80A7-577CF45DFB8AQ33892169-2E60E812-4477-46B8-A1F8-5E9AB06A6729Q33907425-22044753-EE19-47C5-867B-2F1E6FF3B8EDQ34449179-9E7677DE-4236-4A40-9A61-5471AA7FD78DQ34463003-8575BA2E-CAD2-4FFB-9AFA-44E84B568FDB
P2860
Disruptive CHD8 mutations define a subtype of autism early in development
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Disruptive CHD8 mutations define a subtype of autism early in development
@ast
Disruptive CHD8 mutations define a subtype of autism early in development
@en
Disruptive CHD8 mutations define a subtype of autism early in development
@en-gb
Disruptive CHD8 mutations define a subtype of autism early in development
@nl
type
label
Disruptive CHD8 mutations define a subtype of autism early in development
@ast
Disruptive CHD8 mutations define a subtype of autism early in development
@en
Disruptive CHD8 mutations define a subtype of autism early in development
@en-gb
Disruptive CHD8 mutations define a subtype of autism early in development
@nl
prefLabel
Disruptive CHD8 mutations define a subtype of autism early in development
@ast
Disruptive CHD8 mutations define a subtype of autism early in development
@en
Disruptive CHD8 mutations define a subtype of autism early in development
@en-gb
Disruptive CHD8 mutations define a subtype of autism early in development
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Disruptive CHD8 mutations define a subtype of autism early in development
@en
P2093
Anneke T Vulto-van Silfhout
Bert B A de Vries
Bradley P Coe
Carl Baker
David G Amaral
Heather C Mefford
Hilde Peeters
Janneke H Schuurs-Hoeijmakers
Jean Steyaert
P2860
P304
P3181
P356
10.1016/J.CELL.2014.06.017
P407
P50
P5008
P577
2014-07-17T00:00:00Z