Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.
about
Molecular mechanisms of etoposideTDP2 protects transcription from abortive topoisomerase activity and is required for normal neural functionLarge-scale quality analysis of published ChIP-seq data.Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response GenesTopoisomerase 1 inhibition reversibly impairs synaptic function.DNA topoisomerase II is involved in regulation of cyst wall protein genes and differentiation in Giardia lamblia.Topoisomerases facilitate transcription of long genes linked to autismTopoisomerase II beta interacts with cohesin and CTCF at topological domain bordersTopoisomerase II regulates yeast genes with singular chromatin architectures.Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cellsChd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.Embryonic and induced pluripotent stem cell differentiation as a tool in neurobiology.DNA topoisomerases beyond the standard role.Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells.Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program.Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network.Why Cortical Neurons Cannot Divide, and Why Do They Usually Die in the Attempt?Topoisomerases and the regulation of neural function.Nuclear dynamics of topoisomerase IIβ reflects its catalytic activity that is regulated by binding of RNA to the C-terminal domainSpecificity protein 1 regulates topoisomerase IIβ expression in SH-SY5Y cells during neuronal differentiation.The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.Physiological functions of programmed DNA breaks in signal-induced transcription.Mapping gene regulatory circuitry of Pax6 during neurogenesis.Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon.Dynamics and function of distal regulatory elements during neurogenesis and neuroplasticity.Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin.Physiological Roles of DNA Double-Strand Breaks.Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain.Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II.Topoisomerase II Chromatin Immunoprecipitation.Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts.Gene regulation and priming by topoisomerase IIα in embryonic stem cells.Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform.TOP2B: The First Thirty YearsCiprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2
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Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Target genes of Topoisomerase ...... ined by their chromatin state.
@ast
Target genes of Topoisomerase ...... ined by their chromatin state.
@en
type
label
Target genes of Topoisomerase ...... ined by their chromatin state.
@ast
Target genes of Topoisomerase ...... ined by their chromatin state.
@en
prefLabel
Target genes of Topoisomerase ...... ined by their chromatin state.
@ast
Target genes of Topoisomerase ...... ined by their chromatin state.
@en
P2093
P2860
P50
P356
P1476
Target genes of Topoisomerase ...... ined by their chromatin state.
@en
P2093
Antoine H F M Peters
Christian Mielke
Christiane Wirbelauer
Dirk Schübeler
Johannes Kaut
Leslie Hoerner
Lukas Burger
Remi Terranova
Vijay K Tiwari
P2860
P304
P356
10.1073/PNAS.1119798109
P407
P577
2012-04-02T00:00:00Z