The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.
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Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania majorTrypanosoma brucei AMP-activated kinase subunit homologs influence surface molecule expressionLeishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage?High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics.Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness.KREX2 is not essential for either procyclic or bloodstream form Trypanosoma brucei.Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat.Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant.Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylaseSugar nucleotide pools of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major.Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania majorThe de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei.Altered cofactor binding affects stability and activity of human UDP-galactose 4'-epimerase: implications for type III galactosemiaLeishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesisThe synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation.Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation.A Gene of the β3-Glycosyltransferase Family Encodes N-Acetylglucosaminyltransferase II Function in Trypanosoma bruceiFate of glycosylphosphatidylinositol (GPI)-less procyclin and characterization of sialylated non-GPI-anchored surface coat molecules of procyclic-form Trypanosoma brucei.Genetic basis of coaggregation receptor polysaccharide biosynthesis in Streptococcus sanguinis and related species.TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei.Identification of a glycosylphosphatidylinositol anchor-modifying β1-3 galactosyltransferase in Trypanosoma bruceiUDP-xylose and UDP-galactose synthesis in Trichomonas vaginalis.Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicanaTwo functionally divergent UDP-Gal nucleotide sugar transporters participate in phosphoglycan synthesis in Leishmania major.The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases.Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase.Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose.Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei.The glycosylphosphatidylinositol (GPI) biosynthetic pathway of bloodstream-form Trypanosoma brucei is dependent on the de novo synthesis of inositol.Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant.Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease.Identification of a novel UDP-sugar pyrophosphorylase with a broad substrate specificity in Trypanosoma cruzi.The de novo synthesis of GDP-fucose is essential for flagellar adhesion and cell growth in Trypanosoma brucei.UDP-glycosyltransferase genes in trypanosomatid genomes have diversified independently to meet the distinct developmental needs of parasite adaptations.
P2860
Q28550611-D6FDC165-A067-46EB-BC2D-860D32ED4B36Q33489228-F25EBF38-F729-4685-9937-5E9BB0D74916Q33569844-948113A9-9596-446E-96B7-3762360C4F64Q33738172-1A1DC800-E22D-4F70-A683-01CD065AF456Q33954211-9F6B4885-B0AC-41FF-AEAF-E46E1AE30C3FQ34206225-C641DEAF-8366-4DBB-BB6E-54E1606DFAD4Q34229614-25C17B15-884C-492C-9CDD-47C634254C71Q35191010-BBC2F9BD-C85F-467C-B3B1-24BBEFFEB7EFQ35216711-D2F443AD-A211-4A0E-B83F-CEA4A7330CA6Q35724213-31C1B2F8-DBE8-4046-A86B-82C0F2C61470Q35947133-BEEFE1B3-5E10-42D4-9849-473281FAC7FBQ35947298-59BEBB82-0653-406C-937F-EB475D46B247Q36141595-6373D3BF-74DF-42F3-88EA-D7E444F8E520Q36162284-AEB5D8BE-0EDB-46E2-A7CC-E91B334513CCQ36488276-75CF05A4-29D0-463E-8395-70A0CDC418C8Q36701780-5B66BF67-891B-4D8C-8DE4-4F86CC0584C3Q36760357-A42FA71F-865A-401B-B68A-E471780542C1Q37034455-166520AA-28C1-423F-B9D5-0EE5CB93730DQ37355723-CC1F934F-AA32-4006-8F96-02B11817A5AAQ37506811-E6B3D21E-F9A9-473E-B868-1035A1D73269Q39031763-54C8A300-E990-4C71-8265-598DEFAAEB04Q39097406-D59FF5D4-9F6A-4BFE-B402-568126C02DCFQ39353389-8792B64F-329C-4420-ADFD-271DDEEF2B24Q39694165-677D5BAF-8A5A-4838-9F62-0A17B176BD1DQ40161633-EAD8374F-1813-4A82-B168-087A1DD263F8Q41840446-A34C7128-C74B-4C2F-91FE-E6431D079EE8Q41908027-04C8263B-5F30-4307-8920-ACABFE9E9121Q42259106-58103C33-28F8-4ADC-8537-237C2C43D363Q42263917-B36DADAA-73EB-4E37-B32E-0DBC33BA2AEAQ42655247-3568355D-C587-4667-9104-4BFA6A7AADA7Q42663071-AFABB35E-AE93-40E9-ABD9-D3F333ED85A0Q42752718-954B58E4-00AB-4425-AAEF-3B2A48DBF9B2Q43060117-58720A3E-2FCA-4284-9666-E893132A29FCQ46652385-7CAC2441-A6D1-47F6-BE15-41BD027BDE7EQ52655663-C1726F1F-B502-4547-8383-A6D9EBFDE349
P2860
The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The suppression of galactose m ...... ein structure and copy number.
@ast
The suppression of galactose m ...... ein structure and copy number.
@en
type
label
The suppression of galactose m ...... ein structure and copy number.
@ast
The suppression of galactose m ...... ein structure and copy number.
@en
prefLabel
The suppression of galactose m ...... ein structure and copy number.
@ast
The suppression of galactose m ...... ein structure and copy number.
@en
P2093
P2860
P50
P356
P1476
The suppression of galactose m ...... tein structure and copy number
@en
P2093
Irene Hallyburton
James I Macrae
Janine R Roper
M Lucia S Güther
P2860
P304
19728-19736
P356
10.1074/JBC.M502370200
P407
P577
2005-03-14T00:00:00Z