The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.
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Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicityDays to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomersRole of ROS and RNS Sources in Physiological and Pathological ConditionsPrions, prion-like prionoids, and neurodegenerative disordersDissecting Alzheimer disease in Down syndrome using mouse modelsTDP-43: a new player on the AD field?Alzheimer's therapeutics: translation of preclinical science to clinical drug developmentBehavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseEntorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age.Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseSpines, plasticity, and cognition in Alzheimer's model miceInhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model fliesFerulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic micep21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesisDisassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathwaysSelective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodentLoss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.Effects of NK-4 in a transgenic mouse model of Alzheimer's diseaseAmyloid-β oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodiesTau suppression in a neurodegenerative mouse model improves memory functionPaternal spatial training enhances offspring's cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer's mice.Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer.Alzheimer disease: a tale of two prionsMicroglia demonstrate age-dependent interaction with amyloid-β fibrilsExperimental sleep deprivation as a tool to test memory deficits in rodents.APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's diseaseStructural classification of toxic amyloid oligomersAmyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.Reduced IGF-1 signaling delays age-associated proteotoxicity in micePresenilin-2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's diseaseBeta-secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice.Alzheimer disease models and human neuropathology: similarities and differencesIncreased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalitiesHighly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer's disease Tg2576 miceMechanistic and environmental control of the prevalence and lifetime of amyloid oligomersFcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease.Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.
P2860
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P2860
The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The relationship between Abeta ...... model of Alzheimer's disease.
@ast
The relationship between Abeta ...... model of Alzheimer's disease.
@en
type
label
The relationship between Abeta ...... model of Alzheimer's disease.
@ast
The relationship between Abeta ...... model of Alzheimer's disease.
@en
prefLabel
The relationship between Abeta ...... model of Alzheimer's disease.
@ast
The relationship between Abeta ...... model of Alzheimer's disease.
@en
P2093
P921
P1476
The relationship between Abeta ...... e model of Alzheimer's disease
@en
P2093
Ami Mariash
Deirdre Cooper-Blacketer
George A Carlson
Karen H Ashe
Linda H Younkin
Linda Kotilinek
Marcus A Westerman
Steven G Younkin
Takeshi Kawarabayashi
P304
P356
10.1523/JNEUROSCI.22-05-01858.2002
P407
P577
2002-03-01T00:00:00Z