The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation.
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Akt promotes BMP2-mediated osteoblast differentiation and bone developmentGenome-wide analyses of gene expression during mouse endochondral ossificationRegulation of gene expression by PI3K in mouse growth plate chondrocytes.SCF, BDNF, and Gas6 are regulators of growth plate chondrocyte proliferation and differentiation.Loss of the mammalian DREAM complex deregulates chondrocyte proliferationThe effects of physical activity on the epiphyseal growth plates: a review of the literature on normal physiology and clinical implications.Glimepiride promotes osteogenic differentiation in rat osteoblasts via the PI3K/Akt/eNOS pathway in a high glucose microenvironment.Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signalingPlasma C-type natriuretic peptide forms and thyroid status in prepubertal children with acquired thyroid disease.Deletion of the PH-domain and Leucine-rich Repeat Protein Phosphatase 1 (Phlpp1) Increases Fibroblast Growth Factor (Fgf) 18 Expression and Promotes Chondrocyte Proliferation.Effects of In Utero Thyroxine Exposure on Murine Cranial Suture GrowthPromotion of human mesenchymal stem cell osteogenesis by PI3-kinase/Akt signaling, and the influence of caveolin-1/cholesterol homeostasis.Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.Suppression of Nkx3.2 by phosphatidylinositol-3-kinase signaling regulates cartilage development by modulating chondrocyte hypertrophy.Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP.Nitric oxide, C-type natriuretic peptide and cGMP as regulators of endochondral ossification.Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functions.Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes.Current understanding on the molecular basis of chondrogenesis.Chondrocyte hypertrophy in skeletal development, growth, and disease.Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanismHyperbaric oxygen protects mandibular condylar chondrocytes from interleukin-1β-induced apoptosis via the PI3K/AKT signaling pathway.The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo.Vinculin functions as regulator of chondrogenesisControl of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth.Chronic sleep restriction induces changes in the mandibular condylar cartilage of rats: roles of Akt, Bad and Caspase-3.An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis.Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model.Role of interleukin-10 in endochondral bone formation in mice: anabolic effect via the bone morphogenetic protein/Smad pathway.
P2860
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P2860
The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@ast
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@en
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@nl
type
label
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@ast
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@en
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@nl
prefLabel
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@ast
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@en
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@nl
P2860
P356
P1476
The PI3K pathway regulates end ...... c chondrocyte differentiation.
@en
P2093
J Ryan Gillespie
Katie D Hoenselaar
P2860
P2888
P356
10.1186/1471-213X-8-40
P577
2008-04-11T00:00:00Z
P5875
P6179
1000894583