Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
about
Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubismDisruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsChemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative MedicineADP-ribosyltransferases and poly ADP-ribosylationATM Kinase Is Required for Telomere Elongation in Mouse and Human CellsPharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapyTankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin PunctaPARP inhibitor treatment in ovarian and breast cancerPARP inhibition: PARP1 and beyondHypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice.Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathwayPoly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model.Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Proteasome regulation by ADP-ribosylationInsights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomasFluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growthTissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo.Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin.XAV939-mediated ARTD activity inhibition in human MB cell lines.The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocationDual Roles for Membrane Association of Drosophila Axin in Wnt Signaling.E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.Wnt pathway activation by ADP-ribosylation.The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in DrosophilaThe expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series.Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms.Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.Telomere length in reproduction.Tankyrases as drug targets.Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.Tankyrases: structure, function and therapeutic implications in cancer.New directions in poly(ADP-ribose) polymerase biology.Anti-TANKyrase weapons promote myelination.
P2860
Q24299210-ABAF0E6B-F352-40AF-B78B-F3298AA42B51Q24337325-BE03E96C-7750-4851-8326-D58E68C27C29Q26796673-AE05DD70-BA97-425C-8668-9D3070F10155Q28082350-0F212767-2E48-4B24-87A9-68FA105A0A99Q28114948-EE993BDF-26C7-44DC-A1B9-B8FD1AD3E3A8Q28477147-BF0395D9-FBE7-4230-977A-49D45BB959F5Q28550473-CE468D3F-AF56-4B57-B373-588F25880B97Q28741688-A45D228C-EE26-444B-B73D-AA8F2E470CECQ29619617-B97DAF16-F89D-440C-8BC6-57AFCF4084D8Q30434277-1210A11C-2B06-4C62-9683-96B7A41BDE54Q33518305-3BB0FF1E-7232-4614-B5DD-08CB2E1D393FQ33671359-DA06C54A-B83A-4313-B72E-0B3BB811BC04Q33717573-79848B59-5A47-453A-9B14-9F08C32B94F7Q33990112-0B597BBE-19F8-4929-9E47-A1BC77496C3EQ34036523-FDEDFB03-16DD-40FB-8E5F-148AE7C82449Q34299288-39094B9D-D8EA-4096-972B-010EE4190107Q34361226-5AC806D0-F191-4BA1-8042-F2ACCB73ED14Q34482189-D87C85BE-DE3D-4F93-AF3C-D178A72483BEQ34776442-E35A41C8-7CCC-4A80-AF34-0051B8A8CB94Q34981637-0227EFC7-52CC-4C3F-9FC6-B45FB9CF387FQ35008320-9C980DDA-0724-4B24-999B-0CA4B5FEC50FQ35097621-3BE38895-A6FA-497D-A89B-745EB33B6786Q35136575-461423FF-2E54-4F1F-BB41-FC6CDBC72C86Q35593198-9682E769-4BFA-4757-BBAC-26E285670065Q36137822-17375004-4DD8-4E80-B913-1939E7850DFBQ36222110-183B7CD0-AF10-478F-9545-D26F62B1F880Q36562360-23954D62-E510-4CC6-88C4-EC6367000D87Q36871744-6C979C21-9AEB-468B-A9C5-10FDA0B6DC9EQ36921138-E69322D7-FBC3-4494-A779-9987C0709283Q36969275-64902ADC-CB76-41CD-B8E6-DCFA7A2D5682Q37151521-B09853A1-11C2-4FEB-AED7-58242CED1C3DQ37261795-50B5395F-4516-456B-A6EC-625BD2D5B295Q37727996-294421B8-EFB1-4DF0-B57E-D534F5C802C8Q37770152-E3119509-BE28-42E6-8CCC-63D1D67953F1Q38038694-E801DD98-88E6-4F2B-A358-79E7B38F925EQ38104494-ABEDE7A6-97B8-408C-B770-2E44840C59E6Q38191981-D8B7B487-C1E8-4A4E-93E7-AFE0BC348ABFQ38224266-A135C60E-14DE-46A1-8C46-FBC1A13F1E45Q38810648-1FAC70EF-D7A3-4820-8FB6-1056D48CE9FAQ39059942-F6D6DAC0-8F73-4E95-B032-5F268F4C0575
P2860
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@ast
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@en
type
label
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@ast
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@en
prefLabel
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@ast
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@en
P2093
P2860
P1433
P1476
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
@en
P2093
Lino Tessarollo
Samuel W Cushman
Susan J Hsiao
Y Jeffrey Chiang
P2860
P356
10.1371/JOURNAL.PONE.0002639
P407
P577
2008-07-09T00:00:00Z