Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
about
pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegansThe 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymeraseKu is associated with the telomere in mammalsTIN2, a new regulator of telomere length in human cellsIdentification of a novel human tankyrase through its interaction with the adaptor protein Grb14TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpressionRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexPARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformationThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceVault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoTankyrase-1 assembly to large protein complexes blocks its telomeric functionTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2PTOP interacts with POT1 and regulates its localization to telomeresRap1 affects the length and heterogeneity of human telomeresA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsThe formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenanceLoss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubismStructural basis of selective ubiquitination of TRF1 by SCFFbx4Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationTelomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeatsPurification of proteins associated with specific genomic LociSubcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoformsPinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesPOT1 association with TRF2 regulates telomere lengthDisruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroThe human Rap1 protein complex and modulation of telomere lengthTankyrase 1 regulates centrosome function by controlling CPAP stabilityc-Myc interacts with TRF1/PIN2 and regulates telomere lengthInhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1The macro domain is an ADP-ribose binding moduleHuman telomerase and its regulationTankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)Control of human telomere length by TRF1 and TRF2Wnt/beta-catenin signaling and small molecule inhibitorsShelterin complex and associated factors at human telomeres
P2860
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P2860
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@ast
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en-gb
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@nl
type
label
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@ast
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en-gb
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@nl
prefLabel
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@ast
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en-gb
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@nl
P2093
P3181
P1433
P1476
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.282.5393.1484
P407
P577
1998-11-20T00:00:00Z