KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin - Test2 - elhamkhani - TriplyDB

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

http://www.wikidata.org/entity/Q33408107

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The Significance of Ras Activity in Pancreatic Cancer Initiation Genetics and biology of pancreatic ductal adenocarcinoma Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular Origin Genetically engineered mouse models of pancreatic adenocarcinoma Human correlates of provocative questions in pancreatic pathology Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer Somatic mutations in exocrine pancreatic tumors: association with patient survival A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas Clinical, molecular and genetic validation of a murine orthotopic xenograft model of pancreatic adenocarcinoma using fresh human specimens Pathology and molecular genetics of pancreatic neoplasms.Critical role of laser microdissection for genetic, epigenetic and proteomic analyses in pancreatic cancer.Absence of pancreatic intraepithelial neoplasia predicts poor survival after resection of pancreatic cancer.Detection of early-stage pancreatic adenocarcinoma.Mutational analysis of cytocentrifugation supernatant fluid from pancreatic solid mass lesions.Precursor lesions of early onset pancreatic cancer.Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.The added value of using mutational profiling in addition to cytology in diagnosing aggressive pancreaticobiliary disease: review of clinical cases at a single center.Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.Pancreatic cancer genomes: toward molecular subtyping and novel approaches to diagnosis and therapy.A Review of the Current Status and Concept of the Emerging Implications of Zinc and Zinc Transporters in the Development of Pancreatic Cancer.Decreased zinc and downregulation of ZIP3 zinc uptake transporter in the development of pancreatic adenocarcinoma Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.The cytotoxic role of RREB1, ZIP3 zinc transporter, and zinc in human pancreatic adenocarcinoma.Targeting reactive oxygen species in development and progression of pancreatic cancer.Systematic Review and Case Series Report of Acinar Cell Carcinoma of the Pancreas.Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.Modified PNA-PCR method: a convenient and accurate method to screen plasma KRAS mutations of cancer patients.STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.Differentiation of pancreatic ductal adenocarcinoma from chronic pancreatitis by PAM4 immunohistochemistry.Disputed paternity: the uncertain ancestry of pancreatic ductal neoplasia.Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence.Genetic basis of a common tumor origin in the development of pancreatic mixed acinar-neuroendocrine-ductal carcinoma: A case report.Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling.Id3 modulates cellular localization of bHLH Ptf1-p48 protein.Myeloid-derived macrophages and secreted HSP90α induce pancreatic ductal adenocarcinoma development.Multiple KRAS mutations in pancreatic adenocarcinoma: molecular features of neoplastic clones indicate the selection of divergent populations of tumor cells.Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1.

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KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

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2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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KRAS2 mutations in human pancr ...... ncreatic cancer cell of origin

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KRAS2 mutations in human pancr ...... ncreatic cancer cell of origin

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KRAS2 mutations in human pancr ...... ncreatic cancer cell of origin

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Molecular Cancer Research

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KRAS2 mutations in human pancr ...... ncreatic cancer cell of origin

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Chanjuan Shi

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Hirohiko Kamiyama

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James R Eshleman

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Mehtab Khan

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Phillip Lim

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Robert A Anders

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P2860

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Pancreatic cancer.

Progression model for pancreatic cancer.

Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions.

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.

Mouse models of pancreatic cancer: the fur is finally flying!

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

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