The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia - Test2 - elhamkhani - TriplyDB

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

http://www.wikidata.org/entity/Q35663506

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Mouse models of pancreatic cancer Genetically engineered mouse models of pancreatic adenocarcinoma Control of cell identity in pancreas development and regeneration Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models Regulation of Cellular Identity in Cancer Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia A monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeys Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis.KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer.Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia.The secret origins and surprising fates of pancreas tumors KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer.Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style.Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras.A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.Update on pancreatic intraepithelial neoplasia.Sox9: a master regulator of the pancreatic program.Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK Deletion of Rb accelerates pancreatic carcinogenesis by oncogenic Kras and impairs senescence in premalignant lesions.Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia Deploying mouse models of pancreatic cancer for chemoprevention studies Modelling oncogenic Ras/Raf signalling in the mouse.Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway.Expression of the stem cell markers CD133 and nestin in pancreatic ductal adenocarcinoma and clinical relevance.AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.Study human pancreatic cancer in mice: how close are they?Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered KrasG12D;Pdx1-Cre mouse (KC) model The pathobiological impact of cigarette smoke on pancreatic cancer development (review).Genetically engineered mouse models of pancreatic cancer.Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component.Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

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P2860

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

http://www.wikidata.org/entity/Q35663506

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2007 nî lūn-bûn

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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The Nestin progenitor lineage ...... atic intraepithelial neoplasia

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Catherine Carrière

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Daniel S Longnecker

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Elliott S Seeley

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Murray Korc

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Tobias Goetze

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Generalized lacZ expression with the ROSA26 Cre reporter strain

CNS stem cells express a new class of intermediate filament protein

Co-localization of nestin and PDX-1 in small evaginations of the main pancreatic duct in adult rats

Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

AGA technical review on the epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. American Gastroenterological Association.

Targeting cyclooxygenase-2 in human neoplasia: rationale and promise.

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