Physiochemical property space distribution among human metabolites, drugs and toxins.
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionEnhancing adverse drug event detection in electronic health records using molecular structure similarity: application to pancreatitisRadiation metabolomics and its potential in biodosimetryTowards a career in bioinformaticsCombining 2D and 3D in silico methods for rapid selection of potential PDE5 inhibitors from multimillion compounds' repositories: biological evaluation.A physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space.BioSM: metabolomics tool for identifying endogenous mammalian biochemical structures in chemical structure spaceFinding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.Two birds with one stone: doing metabolomics with your proteomics kit.Structural diversity of biologically interesting datasets: a scaffold analysis approach.Combination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5-HT6 Antagonists from Large Commercial Repositories.Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.The Acid/Base Profile of the Human Metabolome and Natural Products.An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolitesA 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs.Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures.In silico-based combinatorial pharmacophore modelling and docking studies of GSK-3β and GK inhibitors of Hippophae.Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries.
P2860
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P2860
Physiochemical property space distribution among human metabolites, drugs and toxins.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Physiochemical property space distribution among human metabolites, drugs and toxins.
@ast
Physiochemical property space distribution among human metabolites, drugs and toxins.
@en
Physiochemical property space distribution among human metabolites, drugs and toxins.
@nl
type
label
Physiochemical property space distribution among human metabolites, drugs and toxins.
@ast
Physiochemical property space distribution among human metabolites, drugs and toxins.
@en
Physiochemical property space distribution among human metabolites, drugs and toxins.
@nl
prefLabel
Physiochemical property space distribution among human metabolites, drugs and toxins.
@ast
Physiochemical property space distribution among human metabolites, drugs and toxins.
@en
Physiochemical property space distribution among human metabolites, drugs and toxins.
@nl
P2860
P1433
P1476
Physiochemical property space distribution among human metabolites, drugs and toxins.
@en
P2093
Varun Khanna
P2860
P2888
P356
10.1186/1471-2105-10-S15-S10
P478
10 Suppl 15
P577
2009-12-03T00:00:00Z
P6179
1027509251