Separating the spindle, checkpoint, and timer functions of BubR1
about
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointThe spindle checkpoint and chromosome segregation in meiosisBub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomesAneuploidy causes premature differentiation of neural and intestinal stem cellsSpindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila.Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acidA conserved arginine-rich motif within the hypervariable N-domain of Drosophila centromeric histone H3 (CenH3) mediates BubR1 recruitmentBubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids.Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans.Cenp-meta is required for sustained spindle checkpointDevelopmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy ModelsRED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.Drosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpoint.Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosisCyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition.Mutual regulation between the spindle checkpoint and APC/C.polo Is Identified as a Suppressor of bubR1 Nondisjunction in a Deficiency Screen of the Third Chromosome in Drosophila melanogaster.Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells.Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1.Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregationThe chromokinesin Klp3a and microtubules facilitate acentric chromosome segregation.A tumor suppressor role of the Bub3 spindle checkpoint protein after apoptosis inhibition.A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1.BUB1 and BUBR1: multifaceted kinases of the cell cycle.Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpointCentrosome and spindle assembly checkpoint loss leads to neural apoptosis and reduced brain size.Aneuploidy in Cancer and Aging.BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication.Three BUB1 and BUBR1/MAD3-related spindle assembly checkpoint proteins are required for accurate mitosis in Arabidopsis.Evidence that the spindle assembly checkpoint does not regulate APC(Fzy) activity in Drosophila female meiosis.Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila.
P2860
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P2860
Separating the spindle, checkpoint, and timer functions of BubR1
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Separating the spindle, checkpoint, and timer functions of BubR1
@ast
Separating the spindle, checkpoint, and timer functions of BubR1
@en
type
label
Separating the spindle, checkpoint, and timer functions of BubR1
@ast
Separating the spindle, checkpoint, and timer functions of BubR1
@en
prefLabel
Separating the spindle, checkpoint, and timer functions of BubR1
@ast
Separating the spindle, checkpoint, and timer functions of BubR1
@en
P2093
P2860
P356
P1476
Separating the spindle, checkpoint, and timer functions of BubR1
@en
P2093
Christophe Lefebvre
Doruk Emre
Mary E Gagou
Roger E Karess
Zohra Rahmani
P2860
P304
P356
10.1083/JCB.200905026
P407
P577
2009-11-01T00:00:00Z