Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.
about
miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB RepairInter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair researchA novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.Base excision repair capacity in informing healthspan.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian CellsAutologous hematopoietic stem cell transplantation in lymphoma patients is associated with a decrease in the double strand break repair capacity of peripheral blood lymphocytesQuantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivoDNA mismatch repair and the DNA damage response.Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.Mass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair of DNA Adducts.Temozolomide in the Era of Precision Medicine.DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9.Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease.Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.How are base excision DNA repair pathways deployed in vivo?Transcriptional mutagenesis reduces splicing fidelity in mammalian cells.Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.Development of a Cell-Based Assay for Measuring Base Excision Repair Responses.Pulmonary Arterial Hypertension Is Associated with Oxidative Stress-induced Genome Instability.Three lessons for genetic toxicology from baseball analytics.Investigating the Generalizability of the MultiFlow® DNA Damage Assay and Several Companion Machine Learning Models with a Set of 103 Diverse Test Chemicals.Fluorescent Probes of DNA Repair.In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities.O6-methylguanine-induced transcriptional mutagenesis reduces p53 tumor-suppressor function.
P2860
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P2860
Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@ast
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@en
type
label
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@ast
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@en
prefLabel
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@ast
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@en
P2093
P2860
P50
P356
P1476
Multiplexed DNA repair assays ...... d transcriptional mutagenesis.
@en
P2093
Anthony L Forget
Anwaar Ahmad
Carrie M Margulies
Leona D Samson
Patrizia Mazzucato
Ryan P Abo
Zachary D Nagel
P2860
P304
P356
10.1073/PNAS.1401182111
P407
P577
2014-04-22T00:00:00Z