Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death
about
GSK-3 as potential target for therapeutic intervention in cancerNKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple MyelomaGSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosisThe intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bortezomib on multiple myeloma and mantle cell lymphoma cells.Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.Kinase inhibitors as potential agents in the treatment of multiple myeloma.Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.The emerging role of GSK-3β in the pathobiology of classical Hodgkin lymphoma.Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer.Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities.The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells.Small molecule enhancers of rapamycin induce apoptosis in myeloma cells via GSK3A/B preferentially within a protective bone marrow microenvironment.[Screening and identification of novel drug-resistant genes in CD133+ and CD133- lung adenosarcoma cells using cDNA microarray].
P2860
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P2860
Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@ast
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@en
type
label
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@ast
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@en
prefLabel
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@ast
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@en
P2093
P2860
P356
P1433
P1476
Glycogen Synthase Kinase-3 reg ...... bortezomib-induced cell death
@en
P2093
Anna Cabrelle
Anna Colpo
Barbara Montini
Carmela Gurrieri
Fausto Adami
Francesco Piazza
Gianpietro Semenzato
Laura Pavan
Laura Quotti Tubi
Livio Trentin
P2860
P2888
P356
10.1186/1471-2407-10-526
P407
P577
2010-10-04T00:00:00Z
P5875
P6179
1033717209