Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling

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Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling

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scientific article published on 21 June 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в червні 2018

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Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly

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Recruitment of ubiquitin-activ ...... ibose) promotes ATR signalling

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Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly

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Recruitment of ubiquitin-activ ...... ibose) promotes ATR signalling

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Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly

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Recruitment of ubiquitin-activ ...... ibose) promotes ATR signalling

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P1476

Recruitment of ubiquitin-activ ...... ibose) promotes ATR signalling

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Christian Larroque

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Marion Larroque

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Ramhari Kumbhar

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Sofia Kossida

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Sophie Vidal-Eychenié

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RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

E3 ligase RFWD3 participates in replication checkpoint control

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

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e201800096

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scholarly article

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10.26508/LSA.201800096

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English

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Cyril Ribeyre

Angelos Constantinou

Dimitrios - Georgios Kontopoulos

Jihane Basbous

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2018-06-21T00:00:00Z

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30456359

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6238597

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