about
A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptorT cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformationPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationInhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domainDimerization of receptor protein-tyrosine phosphatase alpha in living cellsA common model for cytokine receptor activation: combined scissor-like rotation and self-rotation of receptor dimer induced by class I cytokineA crystallographic snapshot of tyrosine trans-phosphorylation in actionA functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptorEvidence for intermolecular interactions between the intracellular domains of the arabidopsis receptor-like kinase ACR4, its homologs and the Wox5 transcription factorSeeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cellsA putative molecular-activation switch in the transmembrane domain of erbB2.The SCHOOL of nature: I. Transmembrane signaling.Exact model reduction of combinatorial reaction networks.The 8p12 myeloproliferative syndrome.Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimersMinireview: Pathophysiological roles of the TR4 nuclear receptor: lessons learned from mice lacking TR4Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog SpitzTrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptorThe sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.Nerve growth factor signals via preexisting TrkA receptor oligomersSmall-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.The SCHOOL of nature: III. From mechanistic understanding to novel therapiesInitiation of TCR signaling: regulation within CD3 dimers.The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1.HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks.Juxtamembrane autoinhibition in receptor tyrosine kinases.Structural modules for receptor dimerization in the S-locus receptor kinase extracellular domain.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397PTPs versus PTKs: the redox side of the coin.Nonmuscle myosin II is required for internalization of the epidermal growth factor receptor and modulation of downstream signaling.The role of VEGF receptors in angiogenesis; complex partnershipsSpectrum of activity and mechanism of action of VEGF/PDGF inhibitors.Identification of in vitro autophosphorylation sites and effects of phosphorylation on the Arabidopsis CRINKLY4 (ACR4) receptor-like kinase intracellular domain: insights into conformation, oligomerization, and activity.Protein intrinsic disorder and oligomericity in cell signaling.The signaling mechanism of eosinophil activation.New therapeutic strategies targeting transmembrane signal transduction in the immune system.TCR Nanoclusters as the Framework for Transmission of Conformational Changes and Cooperativity.Signals and Receptors.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Receptor signaling: when dimerization is not enough.
@ast
Receptor signaling: when dimerization is not enough.
@en
type
label
Receptor signaling: when dimerization is not enough.
@ast
Receptor signaling: when dimerization is not enough.
@en
prefLabel
Receptor signaling: when dimerization is not enough.
@ast
Receptor signaling: when dimerization is not enough.
@en
P1433
P1476
Receptor signaling: when dimerization is not enough.
@en
P2093
P304
P356
10.1016/S0960-9822(99)80357-1
P407
P577
1999-07-01T00:00:00Z