Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.
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Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapyAnimal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for 100 YearsSex-related differences of urethane and sodium valproate effects on Ki-67 expression in urethane-induced lung tumors of miceMatrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formationPI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk22-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.Sodium Valproate Enhances the Urethane-Induced Lung Adenomas and Suppresses Malignization of Adenomas in Ovariectomized Female MiceExpression Profiling Identifies Bezafibrate as Potential Therapeutic Drug for Lung Adenocarcinoma.Targeting oncogenic KRAS in non-small cell lung cancer cells by phenformin inhibits growth and angiogenesisMutant AKT1-E17K is oncogenic in lung epithelial cellsLoss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expressionPI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy.Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancerp27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms.FOXO transcription factors in cancer development and therapy.Sphingomyelin Synthase 1 Regulates Neuro-2a Cell Proliferation and Cell Cycle Progression Through Modulation of p27 Expression and Akt Signaling.Independent and core pathways in oncogenic KRAS signaling.FOXO Signaling Pathways as Therapeutic Targets in Cancer.ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma.Preclinical modeling of EGFR-specific antibody resistance: oncogenic and immune-associated escape mechanisms.Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.The clinicopathological significance of forkhead box P1 and forkhead box O3a in pancreatic ductal adenocarcinomas.Apigenin enhances the cytotoxic effects of tumor necrosis factor-related apoptosis-inducing ligand in human rheumatoid arthritis fibroblast-like synoviocytes.
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P2860
Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@ast
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@en
type
label
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@ast
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@en
prefLabel
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@ast
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@en
P2093
P2860
P356
P1433
P1476
Inhibition of PI-3K restores n ...... el of Kras-driven lung cancer.
@en
P2093
J Philipp-Staheli
K E Gurley
K Hoon-Kim
K S Kelly-Spratt
S Knoblaugh
P2860
P2888
P304
P356
10.1038/ONC.2009.226
P407
P577
2009-08-03T00:00:00Z
P5875
P6179
1018391261