New hedgehog/GLI-signaling inhibitors from Adenium obesum. - Test2 - elhamkhani - TriplyDB

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

http://www.wikidata.org/entity/Q33775728

about

Targeting Gli transcription activation by small molecule suppresses tumor growth.Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.Small molecule Hedgehog pathway antagonists.Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1-DNA-complex formation.Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer.Chemical constituents and biological activities of Adenium obesum (Forsk.) Roem. et Schult.Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.Hh signaling inhibitors from Vitex negundo; naturally occurring inhibitors of the GLI1-DNA complex.In vitro cytotoxic screening of selected Saudi medicinal plants.Hedgehog/GLI-mediated transcriptional activity inhibitors from Crinum asiaticum.Targeting GLI proteins in human cancer by small molecules (WO2014116651 A1): a patent evaluation.Hedgehog signalling pathway inhibitors as cancer suppressing agents

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P2860

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

http://www.wikidata.org/entity/Q33775728

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@ast

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@en

type

label

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@ast

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@en

prefLabel

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@ast

New hedgehog/GLI-signaling inhibitors from Adenium obesum.

@en

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P2860

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P1433

Organic and Biomolecular Chemistry

P1476

New hedgehog/GLI-signaling inhibitors from Adenium obesum

@en

P2093

Chikashi Tateno

http://www.w3.org/2001/XMLSchema#string

Midori A Arai

http://www.w3.org/2001/XMLSchema#string

Seiichiro Kawabe

http://www.w3.org/2001/XMLSchema#string

Takashi Koyano

http://www.w3.org/2001/XMLSchema#string

Thaworn Kowithayakorn

http://www.w3.org/2001/XMLSchema#string

P2860

Small molecule modulation of Smoothened activity

A small molecule that binds Hedgehog and blocks its signaling in human cells

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription.

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

Hedgehog signalling in cancer formation and maintenance.

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.

P304

1133-1139

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1039/C0OB00677G

http://www.w3.org/2001/XMLSchema#string

P433

4

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P478

9

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P50

Masami Ishibashi

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2010-12-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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49695036

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21170436

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