Genomic and epigenetic instability in colorectal cancer pathogenesis.
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Deficient expression of DNA repair enzymes in early progression to sporadic colon cancerHuman colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative statesThe PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cellsMolecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary fieldAn overview of epigenetics and chemopreventionInherited colorectal cancer syndromesCell-based Immunotherapy for Colorectal Cancer with Cytokine-induced Killer CellsThe Diagnostic Performance of Stool DNA Testing for Colorectal Cancer: A Systematic Review and Meta-AnalysisLynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancerMolecular alterations and biomarkers in colorectal cancerEMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer ProgressionMolecular markers for colorectal cancer screeningThe more the messier: centrosome amplification as a novel biomarker for personalized treatment of colorectal cancersMolecular pathogenesis of sporadic colorectal cancersGenetics and Genetic Biomarkers in Sporadic Colorectal CancerDifferences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancerPromoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequenceApoptotic effect of novel Schiff based CdCl₂(C₁₄H₂₁N₃O₂) complex is mediated via activation of the mitochondrial pathway in colon cancer cellsAssessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humansStochastic Tunneling of Two Mutations in a Population of Cancer CellsApplication of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromiumColorectal Carcinoma: A General Overview and Future Perspectives in Colorectal CancerModulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesEnterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.CIMP status of interval colon cancers: another piece to the puzzle.Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo.Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer.Aberrant gene promoter methylation associated with sporadic multiple colorectal cancerArgonaute proteins: potential biomarkers for human colon cancerDistinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci.Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways.Epigenetic silencing of protocadherin 10 in colorectal cancerIntegrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer.The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastasesDNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids.Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancerDifferences in telomerase activity between colon and rectal cancer
P2860
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P2860
Genomic and epigenetic instability in colorectal cancer pathogenesis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@ast
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@en
type
label
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@ast
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@en
prefLabel
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@ast
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@en
P2860
P1433
P1476
Genomic and epigenetic instability in colorectal cancer pathogenesis.
@en
P2093
John M Carethers
William M Grady
P2860
P304
P356
10.1053/J.GASTRO.2008.07.076
P407
P577
2008-09-04T00:00:00Z