Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.
about
Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingConservation of functional domains and limited heterogeneity of HIV-1 reverse transcriptase gene following vertical transmissionIdentification of terminal adenylyl transferase activity of the poliovirus polymerase 3DpolInfluence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selection of their polymerase domainsIllimaquinone, a selective inhibitor of the RNase H activity of human immunodeficiency virus type 1 reverse transcriptaseIsolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptaseInhibition of human immunodeficiency virus type 1 RNase H by sulfated polyanionsTruncating alpha-helix E' of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transferIdentification of functional regions of herpes simplex virus glycoprotein gD by using linker-insertion mutagenesis.The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage siteSubunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase.Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis.Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites.Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.Substitution of a highly basic helix/loop sequence into the RNase H domain of human immunodeficiency virus reverse transcriptase restores its Mn(2+)-dependent RNase H activity.Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H functionReverse transcriptase--a general discussion.RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity.RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-templateMutational analysis of the conserved motifs of influenza A virus polymerase basic protein 1Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.Structure-function studies of HIV reverse transcriptase.Contributions of DNA polymerase subdomains to the RNase H activity of human immunodeficiency virus type 1 reverse transcriptasePurification and characterization of an active human immunodeficiency virus type 1 RNase H domain.Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase.Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1.Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymeraseA general strategy for random insertion and substitution mutagenesis: substoichiometric coupling of trinucleotide phosphoramidites.Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activitiesReconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase.Enzyme activities in four different forms of human immunodeficiency virus 1 pol gene products.Sulphydryl groups in the template-primer-binding domain of murine leukaemia virus reverse transcriptase. Identification and functional analysis of cysteine-90.Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity.Structure-based moloney murine leukemia virus reverse transcriptase mutants with altered intracellular direct-repeat deletion frequencies.Characterization of the protease of a fish retrovirus, walleye dermal sarcoma virus.Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H.Structural models of ribonuclease H domains in reverse transcriptases from retroviruses.Site-directed mutagenesis of the conserved Asp-443 and Asp-498 carboxy-terminal residues of HIV-1 reverse transcriptase.Characterization of the double stranded RNA dependent RNase activity associated with recombinant reverse transcriptases.Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase
P2860
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P2860
Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
name
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@ast
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@en
type
label
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@ast
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@en
prefLabel
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@ast
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@en
P2860
P356
P1476
Linker insertion mutagenesis o ...... the minimal polymerase domain.
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.9.3104
P407
P577
1989-05-01T00:00:00Z