PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis. - Test2 - elhamkhani - TriplyDB

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

http://www.wikidata.org/entity/Q33857705

about

Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA Pathophysiological mechanisms of death resistance in colorectal carcinoma Critical roles of intestinal epithelial vitamin D receptor signaling in controlling gut mucosal inflammation The p53 circuit board p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress Gsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.Increased susceptibility of IDH2-deficient mice to dextran sodium sulfate-induced colitis.Mutant p53 disrupts the stress MAPK activation circuit induced by ASK1-dependent stabilization of Daxx.Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells.PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.Infection-induced bystander-apoptosis of monocytes is TNF-alpha-mediated Tumor necrosis factor-α sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo.Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast Cancer.Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.The BH3-only protein Bad is dispensable for TNF-mediated cell death.AS-IV protects against kidney IRI through inhibition of NF-κB activity and PUMA upregulation Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas.Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma.Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity Rapamycin-resistant and torin-sensitive mTOR signaling promotes the survival and proliferation of leukemic cells.Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκkB-PUMA Signaling.p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis OMP31 of Brucella melitensis 16M impairs the apoptosis of macrophages triggered by TNF-α Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells.

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P2860

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

http://www.wikidata.org/entity/Q33857705

description

2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@ast

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@en

type

label

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@ast

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@en

prefLabel

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@ast

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@en

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Cell Death & Differentiation

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PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.

@en

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C Dudgeon

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G P Zambetti

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H Liu

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P2860

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

Sp1 and p73 activate PUMA following serum starvation

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

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1192-1202

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10.1038/CDD.2009.51

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