PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
about
The Bcl-2 apoptotic switch in cancer development and therapyPUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndromePhosphorylation of Puma modulates its apoptotic function by regulating protein stabilityPUMA, a potent killer with or without p53Sp1 and p73 activate PUMA following serum starvationSMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial eventsSmac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathwayAcute toxicity of the antifouling compound butenolide in non-target organismsThe role of Bcl-x(L) protein in nucleotide excision repair-facilitated cell protection against cisplatin-induced apoptosis.Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells.Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. III. Candidate gene analysis identifies a role for fas in the attenuation of X-ray-induced apoptosisRegorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell deathIn several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute.Correlation between Mcl-1 and pAKT protein expression in colorectal cancer.The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.Lack of association between Bax promoter (-248G>A) single nucleotide polymorphism and susceptibility towards cancer: evidence from a meta-analysis.HER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cellsSynergistic efficacy of a novel combination therapy controls growth of Bcl-x(L) bountiful neuroblastoma cells by increasing differentiation and apoptosis.SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis.The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage.Expression of PUMA in Follicular Granulosa Cells Regulated by FoxO1 Activation During Oxidative Stress.The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growthTumor suppression by resistant maltodextrin, Fibersol-2.Caspase-9 mediates Puma activation in UCN-01-induced apoptosis.Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas.Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.Bcl-2-regulated apoptosis: mechanism and therapeutic potentialGenetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicityDown-regulation of Bax-interacting factor-1 in colorectal adenocarcinomaBcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell deathEWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's SarcomaBax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family membersPUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis.
P2860
Q24620437-32D14B22-48A5-4E79-AE9D-6DB5A8E1450AQ24627524-9D15673B-138A-492E-9CC2-BDE77C1A4660Q24631299-238B0D02-9D17-46E4-8512-7B6D2A8E3682Q24631776-0A13DDB2-744C-41AA-BC0B-3E98C3A5ACECQ24655353-1F4C2245-8B41-4516-8F7B-99D97C304D68Q28284206-00D49673-8F4E-4DC0-B7B3-A1E9B1B9C82DQ28303498-C97175CD-C1B5-40CC-98FF-4952840916D1Q28476733-DB04F3D2-0DEB-4B96-8C1A-289AB7023762Q33421515-FFD89FE3-6DC8-4EAB-87EB-C10D0D71AA69Q33579079-D41C9A0F-3144-43EA-8070-3E65A5421850Q33618734-FC9891FB-48E3-4BF7-977D-0B76187D85ABQ33628461-A6A8013F-94E1-4F62-8896-5CFFE335BA15Q33838524-5D7BF0FF-387A-44D5-AA5E-C4C4E7BA67D8Q33857705-E16D2676-C516-40DA-8B5E-B45E9D0FC1C6Q34168653-6818D45F-5423-454F-8802-A3EAFA653841Q34280884-4776BF5A-4120-461A-B9D4-C0DA42FD1483Q34357910-EF7DB342-9416-4F3B-96C7-3B02A3E05A69Q34389359-1CD8CE77-8D97-422B-8D72-972B2583E5BFQ34876574-D6553A80-0694-46E8-80E5-D34B2A18E346Q34987859-1EA931FC-6848-45BD-9D0E-BE013E8EFE70Q34988091-AED8FB55-17D4-4FB2-9E91-858296088692Q35023204-0D3DBC95-0671-4CC6-9EFB-F559D9B98A19Q35043596-89CD3D99-B317-45E7-97A1-586339504682Q35577785-8E693E71-2CF4-4B31-A2DE-4F3832B18254Q35651474-31052ADE-DB2F-4259-BD9A-CEB309057E0AQ35676779-3642A63E-4D26-4ED4-B8EE-FC9C5DFDD2D5Q35853145-F4479BBC-7CDF-4470-BBB3-08260FB70ADFQ35876786-361B8EF7-0706-4EBF-8B45-709755096578Q35928707-AC5399F0-1F68-4B37-A5DA-2C80B0EEDAB3Q36213081-B27C10CD-ED99-4B77-88B6-739F878274B1Q36291178-50268845-190F-419C-9B4C-00F703CC0282Q36620902-5D86BDCE-C099-40F4-9655-AEF5B2FBCCACQ36836921-0A93D154-E7AC-4855-837F-69A12E129088Q36880621-B83E98A1-32DF-4A46-AB50-90CAB9F82E22Q36920825-4BF2F0F8-194B-4363-9856-ACAE951947D5Q37040018-8F3E5708-41F6-439D-8ED7-84F3A806F1CBQ37112029-0DEC7A09-1113-4540-A8B7-FA2F171BDD5CQ37186651-739399A7-8FBD-44CE-9C91-55AD8FF53576Q37237621-2B824C0C-E7A7-439E-B8E7-4682A8716049Q37246322-AABBDA4B-D0D8-499A-9C62-84B5343D3563
P2860
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@ast
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en-gb
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@nl
type
label
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@ast
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en-gb
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@nl
prefLabel
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@ast
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en-gb
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@nl
P2093
P2860
P921
P3181
P356
P1476
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
@en
P2093
Alexander Bank
Lihua Ming
P2860
P304
16034-16042
P3181
P356
10.1074/JBC.M513587200
P407
P577
2006-04-11T00:00:00Z