p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.
about
Telomeres in Cancer TherapyTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesMammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MTelomere shortening and apoptosis in telomerase-inhibited human tumor cellsRegulation of glucose metabolism by p53: emerging new roles for the tumor suppressorThe telomere syndromesTwo faces of p53: aging and tumor suppressionComplex roles for telomeres and telomerase in breast carcinogenesisA balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytesGenomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerTelomeres in aging and disease: lessons from zebrafishTherapeutic Targeting of TelomeraseTelomeres and telomerase as therapeutic targets to prevent and treat age-related diseasesChanges in Regenerative Capacity through LifespanBiology of telomeres: importance in etiology of esophageal cancer and as therapeutic targetAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionAxis of ageing: telomeres, p53 and mitochondriaOxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegenerationTelomere shortening in human diseasesDisruptive chemicals, senescence and immortalityTherapeutic targeting of replicative immortalityExamination of the expanding pathways for the regulation of p21 expression and activity.Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndromeRegulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainLoss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscleLinking functional decline of telomeres, mitochondria and stem cells during ageingVariation at the TERT locus and predisposition for cancerThe role of telomeres and telomerase in stem cell agingArsenic inhibition of telomerase transcription leads to genetic instabilityRedox regulation of mitochondrial functionChange in peripheral blood leukocyte telomere length and mortality in breast cancer survivorsCell biology of disease: Telomeropathies: an emerging spectrum disorderTelomeres and telomere dynamics: relevance to cancers of the GI tractRecruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastp53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouseProgrammed Death Phenomena: From Organelle to Organism
P2860
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P2860
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@ast
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@en
type
label
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@ast
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@en
prefLabel
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@ast
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@en
P2093
P1433
P1476
p53 deficiency rescues the adv ...... to accelerate carcinogenesis.
@en
P2093
Artandi SE
DePinho RA
Gottlieb GJ
P304
P356
10.1016/S0092-8674(00)80762-X
P407
P577
1999-05-01T00:00:00Z