Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation
about
PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesShelterin complex and associated factors at human telomeresHepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesThe telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p during ribosome biogenesis.Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer.The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in miceZscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase statusPinX1 the tail on the chromosomePinX1: a sought-after major tumor suppressor at human chromosome 8p23Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.The role of PinX1 in growth control of breast cancer cells and its potential molecular mechanism by mRNA and lncRNA expression profiles screening.PinX1: structure, regulation and its functions in cancer.Nuclear condensation and cell cycle arrest induced by telomerase siRNA in neuroblastoma cells.TIN2 stability is regulated by the E3 ligase Siah2.NF-κB potentiates tumor growth by suppressing a novel target LPTS.Telomerase activity and telomere length distribution in vascular endothelial cells in a short-term culture under the presence of hydrogen peroxide.Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition.Telomeres: Implications for Cancer Development.
P2860
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P2860
Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@ast
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en-gb
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@nl
type
label
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@ast
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en-gb
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@nl
prefLabel
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@ast
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en-gb
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@nl
P2093
P2860
P921
P356
P1476
Telomerase inhibitor PinX1 pro ...... to prevent telomere elongation
@en
P2093
Christina Y Soohoo
Kun Ping Lu
Pengyu Huang
Tae Ho Lee
Xiao Zhen Zhou
P2860
P304
P356
10.1074/JBC.M110.180174
P407
P577
2011-02-04T00:00:00Z