A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host.
about
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana.Kinases as druggable targets in trypanosomatid protozoan parasitesRecent developments in drug discovery for leishmaniasis and human African trypanosomiasisEvolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinentTcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi: cloning, trans-splicing, and prenylation studies.Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection.Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage.Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection.Overexpression of a single Leishmania major gene enhances parasite infectivity in vivo and in vitroSubunit vaccination of mice against new world cutaneous leishmaniasis: comparison of three proteins expressed in amastigotes and six adjuvants.Heterogeneity of molecular resistance patterns in antimony-resistant field isolates of Leishmania species from the western Mediterranean area.Leishmania mitochondrial peroxiredoxin plays a crucial peroxidase-unrelated role during infection: insight into its novel chaperone activityIdentification of a disulfide isomerase protein of Leishmania major as a putative virulence factor.Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.Stage-specific requirement of a mitogen-activated protein kinase by Trypanosoma bruceiHeme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.Interacting protein kinases involved in the regulation of flagellar length.Protein kinases as drug targets in trypanosomes and Leishmania.Molecular cloning and characterization of mitogen-activated protein kinase 2 in Trypanosoma cruziHuman p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replicationTrypanosoma brucei: Two mitogen activated protein kinase kinases are dispensable for growth and virulence of the bloodstream formLipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major.Antimony resistance in leishmania, focusing on experimental research.Modulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase.A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation.Central carbon metabolism of Leishmania parasites.Drug targets in Leishmania.Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens.What has proteomics taught us about Leishmania development?Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens?Transferrin: Endocytosis and Cell Signaling in Parasitic Protozoa.MAPK1 of Leishmania donovani interacts and phosphorylates HSP70 and HSP90 subunits of foldosome complex.Catalytic activity of a novel serine/threonine protein phosphatase PP5 from Leishmania major.Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays.Protein kinase involved in flagellar-length control.Two functionally divergent UDP-Gal nucleotide sugar transporters participate in phosphoglycan synthesis in Leishmania major.Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance.Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana.
P2860
Q24815881-51309B92-DE8C-4D1C-AD6D-E8D7A2C1457CQ25257456-D43C696B-0891-494A-BE20-173A1DF5AAE4Q26786761-925E76F2-C32D-44C6-AC82-0378ADDC019AQ27011766-3C968F05-D8C6-4840-8FA2-DEB3A25E79E8Q28551055-14E5C759-B058-4972-91CC-F7574F078193Q30669934-FC5C1AFA-D5E2-4012-8362-2AADA7CA8F30Q33301990-8768B1E0-C46E-4202-BFC9-C5F039CCF99FQ33585885-384696F9-50DC-4A51-A6C0-2A6CBB185531Q33704536-A6A23A48-9662-4DBA-8856-909364D1E6B9Q33903394-C3188807-61F1-4BDC-872B-F213D40BACC5Q34003547-0076DFE6-E175-4601-BBF5-E66232604F76Q34058276-D8BDA8EC-39FE-434D-BFF5-ED2592439C27Q34064205-5C5D5A7E-763E-4323-BCD4-03EF9E497B5EQ34126878-72A0BB80-6D25-4C79-898B-7EAE0BFE8774Q34215427-45D41260-9C70-4B5A-BEA6-99E36E3803C0Q34274140-5DB438BF-CB4E-441D-A1C9-2D26B903BC82Q34341370-F3DC810E-1225-44CE-8BBC-EE67B0905BE1Q34483709-83718B2E-27D0-4AAD-B62D-9546C03CFC66Q34578463-3A06219B-96C4-44FA-A18D-732905CB41BCQ34582170-226AB5DF-C372-463E-B0AF-914F5F4AAE25Q34792290-8CBC4D8A-9414-471C-872A-D597797285F8Q35000637-A0D150AA-FF71-4E00-97C3-800ABDA9BB45Q35202576-85EA01F8-9CC9-4ED9-9F52-A01D7C0B7AE7Q35607561-19EA6461-17CD-4275-AE03-5392DCABEA4CQ36223332-1C728F06-C275-4BB7-BE3E-3EF25343680BQ36227966-C144C4D2-8523-4617-B216-9D080BC6E7F1Q37020701-AC7B5BC3-0A4D-47C4-8762-697F0AFFE592Q37693229-689E82DD-A8B1-4001-9D4F-B0BC2907B2B4Q37869809-732F35B3-F0F4-4F32-900E-38820D484283Q37884396-2EFED48A-F07E-4A78-9DF3-E0495934560AQ37988648-A3D923FA-64A1-4E2D-8D2E-B943D8E4C4C6Q38040818-53661922-C143-4A49-B37F-F91A063CCE1AQ38532065-00B275F7-70C5-455E-9961-8D4F44C91E1EQ39124386-F681AA41-4376-4FF7-8305-A7C04D4D9668Q39181812-296929C2-38D7-4E9F-9467-E12B1C1B7EB4Q39485122-D9E8CDFE-752A-4333-800A-5426FD07C319Q39592103-4A7DCB6F-9AB3-4BB9-B27E-1746FCF2AB47Q40161633-D7085BBF-B282-4897-AC6D-E991D39D3CE7Q40325470-56B35D73-1C04-4CFC-BE77-4CC31F9A7543Q40387461-CA77EF0F-4DAF-4C88-BB0E-2D91AF594A22
P2860
A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A mitogen-activated protein (M ...... survival in the infected host.
@ast
A mitogen-activated protein (M ...... survival in the infected host.
@en
type
label
A mitogen-activated protein (M ...... survival in the infected host.
@ast
A mitogen-activated protein (M ...... survival in the infected host.
@en
prefLabel
A mitogen-activated protein (M ...... survival in the infected host.
@ast
A mitogen-activated protein (M ...... survival in the infected host.
@en
P2860
P921
P356
P1433
P1476
A mitogen-activated protein (M ...... survival in the infected host
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/17.9.2619
P407
P50
P577
1998-05-01T00:00:00Z