The structure of mitogen-activated protein kinase p38 at 2.1-A resolution - Test2 - elhamkhani - TriplyDB

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

http://www.wikidata.org/entity/Q27736668

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Structure prediction and validation of the ERK8 kinase domain The MAP kinase HwHog1 from the halophilic black yeast Hortaea werneckii: coping with stresses in solar salterns A distinct interaction mode revealed by the crystal structure of the kinase p38α with the MAPK binding domain of the phosphatase MKP5 Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions.Druggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe Molecules p38 MAPK in cardioprotection - are we there yet?MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPK Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition Molecular basis of MAPK-activated protein kinase 2:p38 assembly The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer p38α MAP Kinase C-Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38 Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases Sequence Determinants of a Specific Inactive Protein Kinase Conformation Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1 X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors Crystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1 Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1 ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1 Differential regulation and properties of MAPKs Co-conserved MAPK features couple D-domain docking groove to distal allosteric sites via the C-terminal flanking tail ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions A conserved docking motif in MAP kinases common to substrates, activators and regulators Overview of protein structural and functional folds.Overview of protein folds in the immune system.The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding Quantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX.ClustENM: ENM-Based Sampling of Essential Conformational Space at Full Atomic Resolution.How much NMR data is required to determine a protein-ligand complex structure?The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha. Implications for signal/response profiles of MAP kinase pathways.Development of a p38 Kinase Binding Assay for High Throughput Screening.Substrate and docking interactions in serine/threonine protein kinases A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host.Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.Signalling in the yeasts: an informational cascade with links to the filamentous fungi.The p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.Active mutants of the human p38alpha mitogen-activated protein kinase.Recent advances in plant MAP kinase signalling.

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P2860

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

http://www.wikidata.org/entity/Q27736668

description

1997 nî lūn-bûn

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1997 թուականի Մարտին հրատարակուած գիտական յօդուած

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1997 թվականի մարտին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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Proceedings of the National Academy of Sciences of the United States of America

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The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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P2093

E J Goldsmith

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J Han

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M H Cobb

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P C Harkins

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R J Ulevitch

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Z Wang

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P2860

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2

Structural basis of cyclin-dependent kinase activation by phosphorylation

Components of a new human protein kinase signal transduction pathway

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

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2327-32

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scholarly article

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613483

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10.1073/PNAS.94.6.2327

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6

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94

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1997-03-18T00:00:00Z

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14096520

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9122194

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20087

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