Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
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Shortened telomere length is associated with increased risk of cancer: a meta-analysisModeling somatic evolution in tumorigenesisTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationDeletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndromeMolecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targetsMassive genomic rearrangement acquired in a single catastrophic event during cancer developmentTelomere dysfunction and chromosome instabilityCentrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeresSex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cellsDevelopmental context determines latency of MYC-induced tumorigenesisComplex roles for telomeres and telomerase in breast carcinogenesisMapping common deleted regions on 5p15 in cervical carcinoma and their occurrence in precancerous lesions.Models of breast cancer: quo vadis, animal modeling?Mammary epithelial cell transformation: insights from cell culture and mouse models.Telomeres in aging and disease: lessons from zebrafishTherapeutic Targeting of TelomeraseEvaluating biomarkers to model cancer risk post cosmic ray exposureMyosins as fundamental components during tumorigenesis: diverse and indispensableAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionDouble-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instabilityEvolution of the cancer genomeTherapeutic targeting of replicative immortalityProgressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cellsStem cells, senescence, neosis and self-renewal in cancer.Polyploids require Bik1 for kinetochore-microtubule attachment.Telomerase Activation in Hematological MalignanciesAging and radiation: bad companionsMammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityEpithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout miceShort Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishLinking functional decline of telomeres, mitochondria and stem cells during ageingVariation at the TERT locus and predisposition for cancerElevated tolerance to aneuploidy in cancer cells: estimating the fitness effects of chromosome number alterations by in silico modelling of somatic genome evolutionLifetime pesticide use and telomere shortening among male pesticide applicators in the Agricultural Health StudyA novel method for banking stem cells from human exfoliated deciduous teeth: lentiviral TERT immortalization and phenotypical analysisInk4a/Arf expression is a biomarker of agingPredictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limitingDanazol Treatment for Telomere DiseasesTelomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.
P2860
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P2860
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@ast
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@en
type
label
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@ast
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@en
prefLabel
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@ast
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@en
P2093
P356
P1433
P1476
Telomere dysfunction promotes ...... nd epithelial cancers in mice.
@en
P2093
G J Gottlieb
R A DePinho
S E Artandi
P2888
P304
P356
10.1038/35020592
P407
P577
2000-08-01T00:00:00Z
P5875
P6179
1017226982