about
Aconitum and Delphinium sp. alkaloids as antagonist modulators of voltage-gated Na+ channels. AM1/DFT electronic structure investigations and QSAR studiesObstructing toxin pathways by targeted pore blockageTheoretical and simulation studies on voltage-gated sodium channelsAllosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinasesChanging channels in pain and epilepsy: Exploiting ion channel gene therapy for disorders of neuronal hyperexcitabilityCharacterization of the Prokaryotic Sodium Channel NavSp Pore with a Microfluidic Bilayer PlatformSodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care databaseExposure to sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the QResearch primary care databaseModulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsyState-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents.Fluorescence imaging of electrically stimulated cells.An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart.Molecular model of anticonvulsant drug binding to the voltage-gated sodium channel inner pore.Chemical construction and structural permutation of neurotoxic natural product, antillatoxin: importance of the three-dimensional structure of the bulky side chain.Ion channel pharmacology.The roles of sodium channels in nociception: Implications for mechanisms of painAn unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node.The M-superfamily of conotoxins: a review.The twisted side chain of antillatoxin is important for potent toxicity: total synthesis and biological evaluation of antillatoxin and analogues.Inhibitory effects of sodium arsenite and acacia honey on acetylcholinesterase in ratsThe hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria.Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula.Hinge-bending motions in the pore domain of a bacterial voltage-gated sodium channelAn emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancersTarget-Driven Evolution of Scorpion ToxinsAutomated and manual patch clamp data of human induced pluripotent stem cell-derived dopaminergic neuronsVoltage-gated sodium channels and metastatic disease.Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, AntillatoxinIdentification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6.Trafficking and cellular distribution of voltage-gated sodium channels.Voltage-gated sodium channel blockers for the treatment of neuropathic pain.Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigineSodium channel blockers for neuropathic pain.Focusing on new monoamine oxidase inhibitors.Total synthesis and functional analysis of non-ribosomal peptides.Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.Advances in targeting voltage-gated sodium channels with small molecules.Voltage-gated sodium channels: pharmaceutical targets via anticonvulsants to treat epileptic syndromes.Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Voltage-gated sodium channels as therapeutic targets.
@ast
Voltage-gated sodium channels as therapeutic targets.
@en
type
label
Voltage-gated sodium channels as therapeutic targets.
@ast
Voltage-gated sodium channels as therapeutic targets.
@en
prefLabel
Voltage-gated sodium channels as therapeutic targets.
@ast
Voltage-gated sodium channels as therapeutic targets.
@en
P2093
P1433
P1476
Voltage-gated sodium channels as therapeutic targets.
@en
P2093
P304
P356
10.1016/S1359-6446(00)01570-1
P577
2000-11-01T00:00:00Z