The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
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Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer diseaseApolipoprotein E and Alzheimer diseaseNMR Meets Tau: Insights into Its Function and PathologyMolecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and PhosphorylationCharacteristics of Tau and Its Ligands in PET ImagingStructure-based design of non-natural amino-acid inhibitors of amyloid fibril formationEpitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8Tau StructuresBezafibrate administration improves behavioral deficits and tau pathology in P301S micePhosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau proteinTrans-synaptic spread of tau pathology in vivoCritical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease.Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogasterA zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluationPhosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.Novel antibody capture assay for paraffin-embedded tissue detects wide-ranging amyloid beta and paired helical filament-tau accumulation in cognitively normal older adults.Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic miceImmunological memory to hyperphosphorylated tau in asymptomatic individuals.Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model.A nucleated assembly mechanism of Alzheimer paired helical filaments.Hyperphosphorylated tau is elevated in Alzheimer's disease with psychosisMutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filamentsStress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?mNos2 deletion and human NOS2 replacement in Alzheimer disease modelsAxonal inclusions in spinocerebellar ataxia type 3.Tau reduction does not prevent motor deficits in two mouse models of Parkinson's diseaseThe role of tau kinases in Alzheimer's disease.Dimethyl sulfoxide induces both direct and indirect tau hyperphosphorylation.Proteopathic tau seeding predicts tauopathy in vivo.Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry.Neurofibrillary degeneration in amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam. Immunochemical characterization of tau proteins.Induction of intracellular tau aggregation is promoted by α-synuclein seeds and provides novel insights into the hyperphosphorylation of tau.Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathiesCalpain dysregulation in Alzheimer's diseaseFunctional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation.Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's diseaseActivation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.
P2860
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P2860
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The switch of tau protein to a ...... the microtubule binding region
@ast
The switch of tau protein to a ...... the microtubule binding region
@en
type
label
The switch of tau protein to a ...... the microtubule binding region
@ast
The switch of tau protein to a ...... the microtubule binding region
@en
prefLabel
The switch of tau protein to a ...... the microtubule binding region
@ast
The switch of tau protein to a ...... the microtubule binding region
@en
P2093
P2860
P1433
P1476
The switch of tau protein to a ...... the microtubule binding region
@en
P2093
Lichtenberg-Kraag B
Schröter C
Vandermeeren A
P2860
P304
P407
P577
1992-04-01T00:00:00Z