Trans-synaptic spread of tau pathology in vivo - Test2 - elhamkhani - TriplyDB

Trans-synaptic spread of tau pathology in vivo

Trans-synaptic spread of tau pathology in vivo

http://www.wikidata.org/entity/Q28732288

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The spectrum of disease in chronic traumatic encephalopathy Altered ribostasis: RNA-protein granules in degenerative disorders Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds Is tau ready for admission to the prion club?Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease New Features about Tau Function and Dysfunction Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging Insights into Mechanisms of Chronic Neurodegeneration Tau Oligomers: The Toxic Player at Synapses in Alzheimer's Disease Mouse models of frontotemporal dementia Human fetal tau protein isoform: possibilities for Alzheimer's disease treatment Combotherapy and current concepts as well as future strategies for the treatment of Alzheimer's disease Exosomes function in cell-cell communication during brain circuit development Mechanisms of protein seeding in neurodegenerative diseases At the interface of sensory and motor dysfunctions and Alzheimer's disease.Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem The role of tau in neurodegenerative diseases and its potential as a therapeutic target Neurodegenerative diseases: expanding the prion concept Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain.Entorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age.Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models Depletion of microglia and inhibition of exosome synthesis halt tau propagation.Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice Targeting mRNA for Alzheimer's and related dementias.The dendritic hypothesis for Alzheimer's disease pathophysiology.Glaucoma: the retina and beyond Spreading of pathology in neurodegenerative diseases: a focus on human studies Three dimensions of the amyloid hypothesis: time, space and 'wingmen'The preclinical phase of the pathological process underlying sporadic Alzheimer's disease Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities Alzheimer's disease and prion protein The release and trans-synaptic transmission of Tau via exosomes Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration

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Trans-synaptic spread of tau pathology in vivo

http://www.wikidata.org/entity/Q28732288

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2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012 թվականին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Trans-synaptic spread of tau pathology in vivo

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Jessica W Wu

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Karen Duff

http://www.w3.org/2001/XMLSchema#string

Li Liu

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Menno P Witter

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Scott A Small

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Valerie Drouet

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Neuropathological stageing of Alzheimer-related changes

Tau suppression in a neurodegenerative mouse model improves memory function

Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections.

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

Anatomical organization of the parahippocampal-hippocampal network.

The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry.

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.

The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites.

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10.1371/JOURNAL.PONE.0031302

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Catherine Taylor Clelland

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2012-01-01T00:00:00Z

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221812773

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