Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections - Test2 - elhamkhani - TriplyDB

Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections

Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections

http://www.wikidata.org/entity/Q33951938

about

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs.Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract.Animal models for studying female genital tract infection with Chlamydia trachomatis Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.Chlamydia Infection Across Host Species Boundaries Promotes Distinct Sets of Transcribed Anti-Apoptotic Factors.Metabolic crosstalk between host and pathogen: sensing, adapting and competing.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.

P2860

Q31148891-1DB8820B-0A67-4BC4-BDF2-183439BE6714 Q34414371-82600D91-23B5-4C1B-8F09-22BA1EF6FAF9 Q34778494-45E3CDA7-AA03-4CA5-B68C-705AD0D1574A Q35995190-21B569AD-3C7F-4F7C-9698-3604772B84F7 Q36179296-E7B4EEF0-AFAF-4A91-9C98-99DE7CA0C7CD Q36237241-4491A801-370E-4F5A-93E5-D11E17F6E4FF Q36281253-122BE451-4735-4F84-93B3-C5B7D1C59527 Q36827240-FB590C7A-4802-4265-8235-42BF91B24E84 Q36950621-660F1C01-FA49-47DC-B069-9B548A55D15F Q37123840-D4555090-22B3-46E1-87D0-9FF3E9198A07 Q37502917-2D9D15FA-9E49-4FA2-A14C-CBFAF9FED574 Q37663300-D6668354-6EA4-43FD-843A-A78573306DF5 Q37682433-ED939AE6-5996-4CB1-90F8-5F5C8F170092 Q37834944-E6DD0083-D913-4C40-BFBE-30C466C1F786 Q37837875-5E56EB7A-57A0-44CB-B9F0-14EF5193127A Q38763262-D41C22F8-D320-48CF-BD96-94C58E2FCAA5 Q38834935-95A8AC7B-8192-4147-80B1-6459E0C80493 Q39127726-705DA403-8A1F-455C-81EA-A4D091A746CA

P2860

Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections

http://www.wikidata.org/entity/Q33951938

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Compensatory T cell responses ...... lamydia trachomatis infections

@ast

Compensatory T cell responses ...... lamydia trachomatis infections

@en

type

label

Compensatory T cell responses ...... lamydia trachomatis infections

@ast

Compensatory T cell responses ...... lamydia trachomatis infections

@en

prefLabel

Compensatory T cell responses ...... lamydia trachomatis infections

@ast

Compensatory T cell responses ...... lamydia trachomatis infections

@en

P1433

Q33951938-5332FD4A-2F28-4B2B-A413-5D5E1657ABF4

P1476

Q33951938-F1AEFDB5-9749-45E3-8E41-1BF8E540F2FB

P2093

Q33951938-4E57B124-8422-4C59-BD37-77999CBA232A

Q33951938-6F86A18B-88C7-4334-83D5-F330BEAA1192

Q33951938-85A186E3-D570-4FC8-A514-3F2E6136E3F5

Q33951938-990CBD9D-3CCA-4D80-BAC6-43576E6AAE09

Q33951938-EBFC7136-8ED6-4B15-B4E5-CC9DBC8FA6B5

P2860

Q33951938-00258632-0129-4C9F-AA07-9148E067AF56

Q33951938-019D209D-54DC-404F-95B4-D6FDD52DB718

Q33951938-0F101DB2-8920-47AA-BEDF-E5DF580C7C18

Q33951938-17119D14-C19B-4625-8026-AD6B36760514

Q33951938-1C15782A-4F78-4F6C-B5DE-46120FCA8D2C

Q33951938-1C533D66-15F7-4D95-B1BA-C1A343C242CE

Q33951938-24F92B0A-8C0D-4281-93EA-BEC9195B43BA

Q33951938-2CD264A6-999D-4FFF-8000-1820F4C27F28

Q33951938-30D2C50B-2401-4935-9329-854179799295

Q33951938-4133468E-93AA-4FAF-9CE4-C451880C8DD1

P304

Q33951938-B72FE6C5-C67F-4310-B131-FBDB7F571220

P31

Q33951938-FAFA8994-104C-4F00-A590-ABF39866E788

P356

Q33951938-500FA399-E0E0-4993-855B-E7661830F4A3

P433

Q33951938-9B3582E7-0AC2-4C6C-A87B-FC7F53AF2565

P478

Q33951938-4CE1E362-6F7C-4EAB-899F-2A0ED5948940

P50

Q33951938-32E97215-E137-493B-A78D-687FD606F1FD

P577

Q33951938-B2C6B8FD-E74A-4131-B6D8-62F0C77C506B

P5875

Q33951938-9746682E-82FD-4385-B66F-7889CA20965D

P698

Q33951938-2ACF9A4D-1DED-45A9-B594-FC3345BCB8C3

P921

Q33951938-F6277B4E-B7E4-4CF4-89B5-9F6507B1C540

P932

Q33951938-5E1A035D-5014-4D8D-9452-2BCEA96D36BE

P356

JOURNAL.PPAT.1001346

P1433

P1476

Compensatory T cell responses ...... lamydia trachomatis infections

@en

P2093

Amy Rohlfing

http://www.w3.org/2001/XMLSchema#string

Dave C Gondek

http://www.w3.org/2001/XMLSchema#string

Gregory A Taylor

http://www.w3.org/2001/XMLSchema#string

Jörn Coers

http://www.w3.org/2001/XMLSchema#string

Michael N Starnbach

http://www.w3.org/2001/XMLSchema#string

P2860

Crossing the line: selection and evolution of virulence traits

Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains

IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death

Global data on visual impairment in the year 2002

Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

P304

e1001346

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PPAT.1001346

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-06-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51469522

http://www.w3.org/2001/XMLSchema#string

P698

21731484

http://www.w3.org/2001/XMLSchema#string

P921

Chlamydia trachomatis

P932

3121881

http://www.w3.org/2001/XMLSchema#string