IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
about
A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse livercPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatisCellular and Molecular Connections between Autophagy and InflammationChlamydia psittaci: update on an underestimated zoonotic agentIdentification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance systemAutophagy, Immunity, and Microbial AdaptationsAutophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation.The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infectionsInterferon-inducible effector mechanisms in cell-autonomous immunity.Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract.Autophagy facilitates antibody-enhanced dengue virus infection in human pre-basophil/mast cells.IFNγ inhibits the cytosolic replication of Shigella flexneri via the cytoplasmic RNA sensor RIG-I.Chlamydia-specific CD4 T cell clones control Chlamydia muridarum replication in epithelial cells by nitric oxide-dependent and -independent mechanisms.IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteinsSelf and non-self discrimination of intracellular membranes by the innate immune system.Secrets of a successful pathogen: legionella resistance to progression along the autophagic pathway.IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malariaRegulation of chlamydial infection by host autophagy and vacuolar ATPase-bearing organelles.Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infectionPlac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tractUbiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteinsThe immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.IFN-inducible GTPases in host cell defenseChlamydia persistence -- a tool to dissect chlamydia--host interactions.Type I interferons induce autophagy in certain human cancer cell lines.STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy.Chlamydia muridarum-specific CD4 T-cell clones recognize infected reproductive tract epithelial cells in an interferon-dependent fashion.Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseasesAutophagy as an antimicrobial strategy.New function of type I IFN: induction of autophagy.Absence of Specific Chlamydia trachomatis Inclusion Membrane Proteins Triggers Premature Inclusion Membrane Lysis and Host Cell Death.Update on Chlamydia trachomatis Vaccinology.Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.Chlamydia-host cell interaction not only from a bird's eye view: some lessons from Chlamydia psittaci.Subversion of Cell-Autonomous Host Defense by Chlamydia Infection.
P2860
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P2860
IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@ast
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en-gb
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@nl
type
label
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@ast
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en-gb
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@nl
altLabel
IFN-γ-Inducible Irga6 Mediates ...... ydia trachomatis via Autophagy
@en
prefLabel
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@ast
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en-gb
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@nl
P2093
P2860
P3181
P1433
P1476
IFN-gamma-inducible Irga6 medi ...... ydia trachomatis via autophagy
@en
P2093
Hesham M Al-Younes
Jens Zerrahn
Munir A Al-Zeer
Peter R Braun
P2860
P3181
P356
10.1371/JOURNAL.PONE.0004588
P407
P577
2009-01-01T00:00:00Z