Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A. - Test2 - elhamkhani - TriplyDB

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.

http://www.wikidata.org/entity/Q34019744

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Drug-induced reactivation of apoptosis abrogates HIV-1 infection Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Iron metabolism and the innate immune response to infection Toward repurposing ciclopirox as an antibiotic against drug-resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial Translational regulation of HIV-1 replication by HIV-1 Rev cellular cofactors Sam68, eIF5A, hRIP, and DDX3.Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome Advances in iron chelation: an update.A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9 Hepcidin induces HIV-1 transcription inhibited by ferroportin A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.In vitro anti-HIV-1 activity of salicylidene acylhydrazide compounds Development of a sensitive HPLC method to measure in vitro permeability of E- and Z-isomeric forms of thiosemicarbazones in Caco-2 monolayers.Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells Reversible Folding of a β-Hairpin Peptide by a Metal-Chelating Amino Acid.The translation factor eIF5A and human cancer.Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation.Current status of the polyamine research field Role of cellular iron and oxygen in the regulation of HIV-1 infection.Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells.Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis.Immunomodulatory effects of antimicrobial agents. Part II: antiparasitic and antifungal agents.Roles of eukaryotic initiation factor 5A2 in human cancer.HIV-1 replication and latency are regulated by translational control of cyclin T1 A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes.Protein Phosphatase-1 -targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals.The spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5A.Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production.Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.Polyamines and Their Role in Virus Infection.Regulation of gene expression by translation factor eIF5A: Hypusine-modified eIF5A enhances nonsense-mediated mRNA decay in human cells.Polyamine Metabolism and Oxidative Protein Folding in the ER as ROS-Producing Systems Neglected in Virology.In vitro evaluation of ciclopirox as an adjuvant for polymyxin B against gram-negative bacteria.Hypusination of eIF5A as a Target for Antiviral Therapy.

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P2860

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.

http://www.wikidata.org/entity/Q34019744

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Inhibition of HIV-1 gene expre ...... karyotic initiation factor 5A.

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Darlene D'Alliessi Gandolfi

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Deepti Saxena

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Hartmut M Hanauske-Abel

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Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: evidence for direct interaction with the export receptor CRM1

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression

Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A

Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.

Identification and characterization of eukaryotic initiation factor 5A-2

Interaction of eukaryotic initiation factor 5A with the human immunodeficiency virus type 1 Rev response element RNA and U6 snRNA requires deoxyhypusine or hypusine modification

The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription

Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A

Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling

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