Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development. - Test2 - elhamkhani - TriplyDB

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

http://www.wikidata.org/entity/Q35563868

about

eIF5A isoforms and cancer: two brothers for two functions?Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation The effects of aging on the BTBR mouse model of autism spectrum disorder.Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells.Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of Trypanosoma brucei Biological Relevance and Therapeutic Potential of the Hypusine Modification System.Deoxyhypusine Modification of Eukaryotic Translation Initiation Factor 5A (eIF5A) Is Essential for Trypanosoma brucei Growth and for Expression of Polyprolyl-containing Proteins Impact of 4-epi-oxytetracycline on the gut microbiota and blood metabolomics of Wistar rats Polyamine biosynthesis is critical for growth and differentiation of the pancreas.Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development.Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish.Polyamines and their metabolites as diagnostic markers of human diseases.A suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infection Characterization of a novel polyclonal anti-hypusine antibody.A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.Functions of Polyamines in Mammals Polyamines in Eukaryotes, Bacteria, and Archaea.Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.Ser/Thr kinases and polyamines in the regulation of non-canonical functions of elongation factor 1A.Spatiotemporal patterning of polyamines in Drosophila development.Different polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates Tetrahymena thermophila and Paramecium tetaurelia.The Essential Role of Spermidine in Growth of Agrobacterium tumefaciens Is Determined by the 1,3-Diaminopropane Moiety Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus.Comparative proteomic analysis of proteins involved in oocyte meiotic maturation in mice.Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease.

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P2860

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

http://www.wikidata.org/entity/Q35563868

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

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P2093

Jong Hwan Park

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Kazuhiro Nishimura

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Myung Hee Park

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Seung Bum Lee

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P2860

Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.

Cloning and expression of human deoxyhypusine synthase cDNA. Structure-function studies with the recombinant enzyme and mutant proteins

Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification

The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A)

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation

Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2

Hypusine-containing protein eIF5A promotes translation elongation

Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex.

Mmd1p, a novel, conserved protein essential for normal mitochondrial morphology and distribution in the fission yeast Schizosaccharomyces pombe.

eIF5A has a function in the elongation step of translation in yeast.

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