Telomere reduction in human colorectal carcinoma and with ageing.
about
Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy useNormal human chromosomes have long G-rich telomeric overhangs at one endRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresA mammalian factor that binds telomeric TTAGGG repeats in vitroThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationCharacterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosisPOT1 association with TRF2 regulates telomere lengthDeletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndromeHuman telomerase and its regulationAccelerated telomere shortening in response to life stressExtensive telomere repeat arrays in mouse are hypervariableTelomere elongation in immortal human cells without detectable telomerase activityA natural product telomerase activator as part of a health maintenance programTelomeres shorten more slowly in long-lived birds and mammals than in short-lived onesInvolvement of 14-3-3 proteins in nuclear localization of telomeraseRepair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts.Will cloned animals suffer premature aging--the story at the end of clones' chromosomesPotential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function.Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeatsStrict control of telomerase activation using Cre-mediated inversion.New trends in molecular and cellular biomarker discovery for colorectal cancerMultiple facets of TPP1 in telomere maintenanceAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionAxis of ageing: telomeres, p53 and mitochondriaT cell replicative senescence in human agingStructure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteinsSenescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.Plasmodium falciparum telomerase: de novo telomere addition to telomeric and nontelomeric sequences and role in chromosome healingFunctional requirement of p23 and Hsp90 in telomerase complexesRegulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainAgeing and telomeres: a study into organ- and gender-specific telomere shorteningShort Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishAccumulation of senescent cells in mitotic tissue of aging primatesVariation at the TERT locus and predisposition for cancerTelomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantationSomatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesisMyc activates telomeraseMalignant transformation potentials of human umbilical cord mesenchymal stem cells both spontaneously and via 3-methycholanthrene inductionA highly selective telomerase inhibitor limiting human cancer cell proliferation
P2860
Q21090806-C95090D5-D5E3-467E-A034-AF98EC8274DCQ22065787-EB8B5F79-AE2D-48B6-A77F-6BE360A44787Q24291989-8A3B854C-67C1-4FFC-8702-C9A87A0EF155Q24293724-8E521097-ED64-4239-AAEC-A9087C55426EQ24306780-F7BF8D90-EA43-4BEB-83D6-3872CFBD6DB1Q24310189-F88601A5-389B-4DAC-83BA-DA13A22321BCQ24311518-6CC75E76-CE3E-4864-9CDF-D827D4D2C25BQ24320254-EC98C706-DA34-43EE-B3E7-0F5C9D6A0A02Q24532112-040354EC-DD6F-4C45-8C2A-3A1F5AB2D068Q24533247-7313EC0B-5F12-471A-AFA5-936E185AAE9FQ24559314-0324BC62-CFE3-45DF-9625-7E1DDB547D26Q24595952-545F33D9-0FFA-4FC6-9DAB-D648BFD1EDFFQ24598626-34F8A08E-359D-4E99-82B3-0288780787E2Q24613834-88DF8731-EF24-4AB9-9392-07F1AC75E934Q24678913-F0397F4B-6E41-4A0A-B551-B47C9BAD569FQ24685623-DBB2EDFD-8F79-462A-B2A8-E60D805B6328Q24796117-E4DF8AE7-4EA9-4D18-BF35-D7BB6E62AB1CQ24801090-B06193AD-F17C-41DB-9766-806C4817ACA7Q24804197-F617B9AE-BF64-4611-B9DE-7D8FC755619AQ24811877-34DD8CC9-C555-4643-9815-CDC564487319Q25257517-C11F31D1-2C9C-4135-ACBC-6A4DB339740CQ26739049-F44CD703-42BA-481E-A925-E9C8C8C52009Q26859063-EB2C05BD-384E-4336-94C6-0A402E5BDA5CQ26862886-61E7B388-A81A-4E54-A693-E6B56300D66AQ26865873-DE562D2E-7DD0-4412-88A2-771D28F7AE7CQ27022690-CD4D468B-273E-420F-88E0-7F1559FB54CDQ27650163-783E383B-ED4E-42D3-B2F9-FC66753487E2Q27931258-1C5FCF3B-D043-4BA7-880E-A53CC309DB7AQ27974791-C6FB4AAA-050A-4F23-9C48-514052A57695Q28115669-0E7070C9-1696-46B3-AEE2-70B76D41D3CAQ28119138-D3A5999F-BEBC-44C4-8878-B82D38DFD061Q28210726-5FF8D75D-03D0-432E-94C1-868737BAC48FQ28272305-3434871B-99F7-4BC9-99AC-DE7A4A2B6649Q28274849-8823C750-38A2-4386-AA4F-57D6A4A5D059Q28282704-133DAA95-7AEB-49D7-ABA6-E0FE4ABBA73BQ28365267-2DA44E4A-FD26-453B-8581-C0DE7113CD80Q28385225-C9C425B2-242E-4997-B9FF-10F0EC0F884EQ28505489-A8BC164B-4182-42B9-BCF2-CC211451646DQ28536701-C27FBD20-7729-4FBA-9963-68DD5E819665Q29301431-C6081CCD-EFAE-48E8-A948-3EF4E91D5910
P2860
Telomere reduction in human colorectal carcinoma and with ageing.
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Telomere reduction in human colorectal carcinoma and with ageing.
@ast
Telomere reduction in human colorectal carcinoma and with ageing.
@en
Telomere reduction in human colorectal carcinoma and with ageing.
@nl
type
label
Telomere reduction in human colorectal carcinoma and with ageing.
@ast
Telomere reduction in human colorectal carcinoma and with ageing.
@en
Telomere reduction in human colorectal carcinoma and with ageing.
@nl
prefLabel
Telomere reduction in human colorectal carcinoma and with ageing.
@ast
Telomere reduction in human colorectal carcinoma and with ageing.
@en
Telomere reduction in human colorectal carcinoma and with ageing.
@nl
P2093
P356
P1433
P1476
Telomere reduction in human colorectal carcinoma and with ageing.
@en
P2093
P2888
P304
P356
10.1038/346866A0
P407
P577
1990-08-01T00:00:00Z
P5875
P6179
1018633124