The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity
about
Unwinding and rewinding: double faces of helicase?Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease researchDeletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast.Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivoPif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal.Inactivation of Pif1 helicase causes a mitochondrial myopathy in miceUnwinding the functions of the Pif1 family helicases.Reconstitution of eukaryotic lagging strand DNA replication.Pif1 regulates telomere length by preferentially removing telomerase from long telomere endsG-quadruplex nucleic acids and human diseaseMitochondrial helicases and mitochondrial genome maintenanceA genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1Telomeres: structures in need of unwinding.The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.Determination of the biochemical properties of full-length human PIF1 ATPase.Borrowing nuclear DNA helicases to protect mitochondrial DNA.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.Roles of Pif1-like helicases in the maintenance of genomic stability.DNA repair at telomeres: keeping the ends intact.Biochemical analysis of human PIF1 helicase and functions of its N-terminal domain.Telomeres do the (un)twist: helicase actions at chromosome termini.The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoG-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction.Telomerase is essential to alleviate pif1-induced replication stress at telomeres.Regulation of telomere addition at DNA double-strand breaks.To peep into Pif1 helicase: multifaceted all the way from genome stability to repair-associated DNA synthesis.G-quadruplex interacting small molecules and drugs: from bench toward bedside.Mitochondrial DNA maintenance: an appraisal.Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases.Characterization of the 5'-flanking region of the human DNA helicase B (HELB) gene and its response to trans-Resveratrol.Getting it done at the ends: Pif1 family DNA helicases and telomeres.Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress.The functions of the multi-tasking Pfh1Pif1 helicase.Solving the Telomere Replication Problem.De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks.Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks.The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA.Telomerase regulation by the Pif1 helicase: a length-dependent effect?Literature and patent analysis of the cloning and identification of human functional genes in China.
P2860
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P2860
The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity
description
2006 nî lūn-bûn
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name
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@ast
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en-gb
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@nl
type
label
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@ast
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en-gb
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@nl
prefLabel
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@ast
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en-gb
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@nl
P2093
P2860
P921
P3181
P356
P1476
The human Pif1 helicase, a pot ...... , inhibits telomerase activity
@en
P2093
Deng-Hong Zhang
Jin-Qiu Zhou
P2860
P304
P3181
P356
10.1093/NAR/GKL029
P407
P577
2006-01-01T00:00:00Z