about
Higher-order multicomponent reactions: beyond four reactants.Stochastic voyages into uncharted chemical space produce a representative library of all possible drug-like compounds.A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.Balancing novelty with confined chemical space in modern drug discovery.Concise synthesis of rare pyrido[1,2-a]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen.A one-pot, three-step process for the diastereoselective synthesis of aminobicyclo[4.3.0]nonanes using consecutive palladium(II)- and ruthenium(II)-catalysis.A Multidimensional Diversity-Oriented Synthesis Strategy for Structurally Diverse and Complex MacrocyclesFast & easy preparation of 3D scaffolds from methyl benzoate by a diversity oriented synthesis strategy based on Diels-Alder and ene-reactions.Modular, One-Pot, Sequential Aziridine Ring Opening-S(N)Ar Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams.A conceptual framework for analysing and planning synthetic approaches to diverse lead-like scaffolds.Biomimetic Assembly Lines Producing Natural Product Analogs: Strategies from a Versatile Manifold to Skeletally Diverse Scaffolds.Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds.Flexible access to conformationally-locked bicyclic morpholines.Diversification of ortho-Fused Cycloocta-2,5-dien-1-one Cores and Eight- to Six-Ring Conversion by σ Bond C-C Cleavage.Generation of molecular complexity from cyclooctatetraene using dienyliron and olefin metathesis methodology.Discovery of a multi-bond forming, four-step tandem process: construction of drug-like polycyclic scaffoldsRecent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Towards the systematic exploration of chemical space.
@ast
Towards the systematic exploration of chemical space.
@en
Towards the systematic exploration of chemical space.
@en-gb
Towards the systematic exploration of chemical space.
@nl
type
label
Towards the systematic exploration of chemical space.
@ast
Towards the systematic exploration of chemical space.
@en
Towards the systematic exploration of chemical space.
@en-gb
Towards the systematic exploration of chemical space.
@nl
prefLabel
Towards the systematic exploration of chemical space.
@ast
Towards the systematic exploration of chemical space.
@en
Towards the systematic exploration of chemical space.
@en-gb
Towards the systematic exploration of chemical space.
@nl
P2093
P2860
P356
P1476
Towards the systematic exploration of chemical space.
@en
P2093
Francesco Marchetti
Martin Fisher
Thomas James
P2860
P356
10.1039/C1OB06098H
P50
P577
2011-10-04T00:00:00Z