about
Identification of direct protein targets of small moleculesPrivileged scaffolds for library design and drug discoverySynthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitorsCytological profiling: providing more haystacks for chemists' needles.Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsStructure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3βDiversity-oriented synthesis yields novel multistage antimalarial inhibitorsChemogenomics: an emerging strategy for rapid target and drug discoverySmall molecules: the missing link in the central dogmaTowards the optimal screening collection: a synthesis strategyOxidative diversification of amino acids and peptides by small-molecule iron catalysisNatural products as sources of new drugs over the 30 years from 1981 to 2010Highly stereoselective synthesis of natural-product-like hybrids by an organocatalytic/multicomponent reaction sequence.A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators.Diversity-oriented synthesis: exploring the intersections between chemistry and biology.Solution-phase synthesis of a tricyclic pyrrole-2-carboxamide discovery library applying a stetter-Paal-Knorr reaction sequenceFluorous mixture synthesis of two libraries with hydantoin-, and benzodiazepinedione-fused heterocyclic scaffolds.A unified synthetic approach to polyketides having both skeletal and stereochemical diversity.Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries.Applications of multicomponent reactions to the synthesis of diverse heterocyclic scaffoldsStrategies for innovation in multicomponent reaction design.Using biological performance similarity to inform disaccharide library design.Design and synthesis of a library of tetracyclic hydroazulenoisoindoles.Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis.Construction of a bicyclic beta-benzyloxy and beta-hydroxy amide library through a multicomponent cyclization reactionStereoselective synthesis of spirocyclic oxindoles via Prins cyclizations.Principles, implementation, and application of biology-oriented synthesis (BIOS).The Privileged Chemical Space Predictor (PCSP): a computer program that identifies privileged chemical space from screens of modularly assembled chemical libraries.The tert-butylsulfinamide lynchpin in transition-metal-mediated multiscaffold library synthesis.A systems biology approach to dissection of the effects of small bicyclic peptidomimetics on a panel of saccharomyces cerevisiae mutants.Probing chemical space with alkaloid-inspired libraries.Studies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofuransStereoselective synthesis of spirooxindole amides through nitrile hydrozirconationRegional Multiteam Systems in Cancer Care Delivery.Diversity through a branched reaction pathway: generation of multicyclic scaffolds and identification of antimigratory agents.Design, synthesis, and biological evaluation of a biyouyanagin compound libraryIncreased diversity of libraries from libraries: chemoinformatic analysis of bis-diazacyclic libraries.Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity.Creation and manipulation of common functional groups en route to a skeletally diverse chemical libraryDiversity-oriented synthesis of macrocyclic peptidomimetics.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A planning strategy for diversity-oriented synthesis
@ast
A planning strategy for diversity-oriented synthesis
@en
A planning strategy for diversity-oriented synthesis
@nl
type
label
A planning strategy for diversity-oriented synthesis
@ast
A planning strategy for diversity-oriented synthesis
@en
A planning strategy for diversity-oriented synthesis
@nl
prefLabel
A planning strategy for diversity-oriented synthesis
@ast
A planning strategy for diversity-oriented synthesis
@en
A planning strategy for diversity-oriented synthesis
@nl
P356
P1476
A planning strategy for diversity-oriented synthesis
@en
P2093
Martin D Burke
Stuart L Schreiber
P356
10.1002/ANIE.200300626
P407
P577
2004-01-01T00:00:00Z