The role of zinc ions in reverse transport mediated by monoamine transporters.
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How addictive drugs disrupt presynaptic dopamine neurotransmissionStudies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine releaseThe N terminus of monoamine transporters is a lever required for the action of amphetaminesThe high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology modelThe mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transportersN,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.Amphetamines, new psychoactive drugs and the monoamine transporter cycle.Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux.The solute carrier 6 family of transportersImportance of cholesterol in dopamine transporter function.Engineered zinc-binding sites confirm proximity and orientation of transmembrane helices I and III in the human serotonin transporter.Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters.Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango.Dopamine release mediated by the dopamine transporter, facts and consequences.Phospho-specific antibodies targeting the amino terminus of the human dopamine transporter.Impact of disruption of secondary binding site S2 on dopamine transporter function.Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters.A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1.Effects of zinc ex vivo on taurine uptake in goldfish retinal cells.Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters.Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter.Occupancy of the Zinc-binding Site by Transition Metals Decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism.Zinc potentiates an uncoupled anion conductance associated with the dopamine transporter.Zinc modulation of serotonin uptake in the adult rat corpus callosum.Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand.
P2860
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P2860
The role of zinc ions in reverse transport mediated by monoamine transporters.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The role of zinc ions in reverse transport mediated by monoamine transporters.
@ast
The role of zinc ions in reverse transport mediated by monoamine transporters.
@en
The role of zinc ions in reverse transport mediated by monoamine transporters.
@nl
type
label
The role of zinc ions in reverse transport mediated by monoamine transporters.
@ast
The role of zinc ions in reverse transport mediated by monoamine transporters.
@en
The role of zinc ions in reverse transport mediated by monoamine transporters.
@nl
prefLabel
The role of zinc ions in reverse transport mediated by monoamine transporters.
@ast
The role of zinc ions in reverse transport mediated by monoamine transporters.
@en
The role of zinc ions in reverse transport mediated by monoamine transporters.
@nl
P2860
P50
P356
P1476
The role of zinc ions in reverse transport mediated by monoamine transporters
@en
P2093
Ernst A Singer
Lene Nørregaard
P2860
P304
21505-21513
P356
10.1074/JBC.M112265200
P407
P577
2002-04-08T00:00:00Z