Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.
about
Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DATMechanisms of dopamine transporter regulation in normal and disease statesX-ray structure of dopamine transporter elucidates antidepressant mechanismDesigning modulators of monoamine transporters using virtual screening techniquesBehavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporterNeurotransmitter and psychostimulant recognition by the dopamine transporter.The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitorsMapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular DynamicsThermal Stability of Dopamine Transporters.2-Substituted 3β-Aryltropane Cocaine Analogs Produce Atypical Effects without Inducing Inward-Facing Dopamine Transporter Conformations.SLC6 transporters: structure, function, regulation, disease association and therapeuticsRegulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease.Interaction of tyrosine 151 in norepinephrine transporter with the 2β group of cocaine analog RTI-113.Temporal expression of mutant LRRK2 in adult rats impairs dopamine reuptakeDecreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.Sigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid.Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrinAmphetamines, new psychoactive drugs and the monoamine transporter cycle.Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.Single molecule analysis of serotonin transporter regulation using antagonist-conjugated quantum dots reveals restricted, p38 MAPK-dependent mobilization underlying uptake activation.Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelopeImportance of cholesterol in dopamine transporter function.Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.A role for sigma receptors in stimulant self-administration and addiction.Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphateDifferential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons.2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter.The dopamine transporter role in psychiatric phenotypes.HIV, Tat and dopamine transmission.Can Cholesterol Metabolism Modulation Affect Brain Function and Behavior?Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol.Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer.Single-quantum-dot tracking reveals altered membrane dynamics of an attention-deficit/hyperactivity-disorder-derived dopamine transporter coding variant.Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes.Palmitoylation mechanisms in dopamine transporter regulation.Recent advances in nanodisc technology for membrane protein studies (2012-2017).Regulation of the Ca(2+)-ATPase by cholesterol: a specific or non-specific effect?Radioligand binding to nanodisc-reconstituted membrane transporters assessed by the scintillation proximity assayDopamine transporter is enriched in filopodia and induces filopodia formation.
P2860
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P2860
Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Membrane cholesterol modulates ...... er and alters cocaine binding.
@ast
Membrane cholesterol modulates ...... er and alters cocaine binding.
@en
Membrane cholesterol modulates ...... er and alters cocaine binding.
@nl
type
label
Membrane cholesterol modulates ...... er and alters cocaine binding.
@ast
Membrane cholesterol modulates ...... er and alters cocaine binding.
@en
Membrane cholesterol modulates ...... er and alters cocaine binding.
@nl
prefLabel
Membrane cholesterol modulates ...... er and alters cocaine binding.
@ast
Membrane cholesterol modulates ...... er and alters cocaine binding.
@en
Membrane cholesterol modulates ...... er and alters cocaine binding.
@nl
P2860
P356
P1476
Membrane cholesterol modulates ...... ter and alters cocaine binding
@en
P2093
Weimin C Hong
P2860
P304
32616-32626
P356
10.1074/JBC.M110.150565
P407
P50
P577
2010-08-05T00:00:00Z