about
BRCA2 and homologous recombinationBRCA1 interacts with FHL2 and enhances FHL2 transactivation functionBRCA1 affects global DNA methylation through regulation of DNMT1Roles of BRCA1 in centrosome duplicationHighlight: BRCA1 and BRCA2 proteins in breast cancerBRCA1 mediates ligand-independent transcriptional repression of the estrogen receptorA requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpointUnbalanced replication as a major source of genetic instability in cancer cellsDegradation of transcription repressor ZBRK1 through the ubiquitin-proteasome pathway relieves repression of Gadd45a upon DNA damageJunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interactionExpression of glucocorticoid and progesterone nuclear receptor genes in archival breast cancer tissueInvestigation of glutathione S-transferase zeta and the development of sporadic breast cancerFrom systems to structure: bridging networks and mechanismM phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complexThe RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutationNFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage responseHuman Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune responseGenetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closureThe yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.A delayed chemically induced tumorigenesis in Brca2 mutant mice.Contribution of germline BRCA1 and BRCA2 sequence alterations to breast cancer in Northern India.BRCA1 and BRCA2 germline mutation analysis in the Indonesian population.The UPS: a promising target for breast cancer treatment.Targeting tumor suppressor networks for cancer therapeutics.Derepression of HMGA2 via removal of ZBRK1/BRCA1/CtIP complex enhances mammary tumorigenesis.Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells.Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression.Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implicationsHeregulin-dependent delay in mitotic progression requires HER4 and BRCA1.Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform.Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform.Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate TumorsBRCA1, hormone, and tissue-specific tumor suppressionBRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity.Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targetsThree-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-RasFood sources of fat and sex hormone receptor status of invasive breast tumors in women of the Malmö Diet and Cancer cohort.BRCA1 suppresses osteopontin-mediated breast cancer.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Lessons learned from BRCA1 and BRCA2.
@ast
Lessons learned from BRCA1 and BRCA2.
@en
Lessons learned from BRCA1 and BRCA2.
@nl
type
label
Lessons learned from BRCA1 and BRCA2.
@ast
Lessons learned from BRCA1 and BRCA2.
@en
Lessons learned from BRCA1 and BRCA2.
@nl
prefLabel
Lessons learned from BRCA1 and BRCA2.
@ast
Lessons learned from BRCA1 and BRCA2.
@en
Lessons learned from BRCA1 and BRCA2.
@nl
P2093
P2860
P356
P1433
P1476
Lessons learned from BRCA1 and BRCA2.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203968
P407
P577
2000-12-01T00:00:00Z
P5875
P6179
1019735201