about
Psychedelics and Immunomodulation: Novel Approaches and Therapeutic OpportunitiesStochastic gene expression in mammals: lessons from olfactionRegulation of type I interferon responsesKeeping it quiet: chromatin control of gammaherpesvirus latencyHeterogeneity in immune responses: from populations to single cellsCollaboration of Toll-like and RIG-I-like receptors in human dendritic cells: tRIGgering antiviral innate immune responsesTools for Single-Cell Kinetic Analysis of Virus-Host InteractionsImpact of Viral Infections on Hematopoiesis: From Beneficial to Detrimental Effects on Bone Marrow OutputInfluenza virus activation of the interferon systemSingle-cell transcriptomics reveals bimodality in expression and splicing in immune cellsModel-based simulation and prediction of an antiviral strategy against influenza A infection.Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response.End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.A new efficient approach to fit stochastic models on the basis of high-throughput experimental data using a model of IRF7 gene expression as case study.Epigenetic control of immunityHigh-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster.Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.Nucleosomes are stably evicted from enhancers but not promoters upon induction of certain pro-inflammatory genes in mouse macrophages.Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.Fluorescence-Activated Cell Sorting-Based Analysis Reveals an Asymmetric Induction of Interferon-Stimulated Genes in Response to Seasonal Influenza A VirusMacrophage Polarization in Virus-Host InteractionsA RIG-I 2CARD-MAVS200 Chimeric Protein Reconstitutes IFN-β Induction and Antiviral Response in Models Deficient in Type I IFN Response.Individual T helper cells have a quantitative cytokine memoryAG490 and PF431396 Sensitive Tyrosine Kinase Control the Population Heterogeneity of Basal STAT1 Activity in Ube1l Deficient CellsGene Expression Correlates with the Number of Herpes Viral Genomes Initiating Infection in Single Cells.β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding SitesShaping the murine macrophage phenotype: IL-4 and cyclic AMP synergistically activate the arginase I promoter.Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response.Innate detection of hepatitis B and C virus and viral inhibition of the response.Quantitative profiling of innate immune activation by viral infection in single cells.Multilayered regulations of RIG-I in the anti-viral signaling pathway.Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.Type I Interferon-Mediated Induction of Antiviral Genes and Proteins Fails to Protect Cells from the Cytopathic Effects of Sendai Virus Infection.Cutting Edge: IFN-β Expression in the Spleen Is Restricted to a Subpopulation of Plasmacytoid Dendritic Cells Exhibiting a Specific Immune Modulatory Transcriptome Signature.Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation.Flow Cytometric Characterization of Antigen-Specific T Cells Based on RNA and Its Advantages in Detecting Infections and Immunological Disorders.Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection.Integrated modeling and analysis of intracellular and intercellular mechanisms in shaping the interferon response to viral infection.Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Stochastic expression of the interferon-β gene.
@ast
Stochastic expression of the interferon-β gene.
@en
Stochastic expression of the interferon-β gene.
@nl
type
label
Stochastic expression of the interferon-β gene.
@ast
Stochastic expression of the interferon-β gene.
@en
Stochastic expression of the interferon-β gene.
@nl
prefLabel
Stochastic expression of the interferon-β gene.
@ast
Stochastic expression of the interferon-β gene.
@en
Stochastic expression of the interferon-β gene.
@nl
P2093
P2860
P1433
P1476
Stochastic expression of the interferon-β gene.
@en
P2093
Hemali Phatnani
Jiangwen Zhang
Mingwei Zhao
P2860
P304
P356
10.1371/JOURNAL.PBIO.1001249
P407
P577
2012-01-24T00:00:00Z