EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.

EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.

Item
http://www.wikidata.org/entity/Q34149887
Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models.Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancerOncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway.Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axisOncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling.Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.RGD and NGR modified TRAIL protein exhibited potent anti-metastasis effects on TRAIL-insensitive cancer cells in vitro and in vivo.IgG-single-chain TRAIL fusion proteins for tumour therapy.Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps.
P2860

EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.

Item
http://www.wikidata.org/entity/Q34149887
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@ast
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@en
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@nl
type
label
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@ast
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@en
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@nl
prefLabel
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@ast
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@en
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@nl
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P1476
EGFR-targeted TRAIL and a Smac ...... utant colorectal cancer cells.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0107165
P407
P433
P478
P50
P577
P5875
P698
P921
P932