Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

Item
http://www.wikidata.org/entity/Q34159860
Optimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolitesKey Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate BiasStructural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenaseImprovement of biocatalysts for industrial and environmental purposes by saturation mutagenesisDrug Oxidation by Cytochrome P450BM3 : Metabolite Synthesis and Discovering New P450 Reaction Types.Drug metabolism in microorganisms.Human Cytochrome P450 3A4 as a Biocatalyst: Effects of the Engineered Linker in Modulation of Coupling Efficiency in 3A4-BMR Chimeras.Design and engineering of artificial oxygen-activating metalloenzymes.Progress in biopharmaceutical development.The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac.Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450 VariantBenzylic hydroxylation of aromatic compounds by P450 BM3
P2860

Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

Item
http://www.wikidata.org/entity/Q34159860
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@ast
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@en
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@nl
type
label
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@ast
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@en
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@nl
prefLabel
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@ast
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@en
Identification of mutant Asp25 ...... ac, ibuprofen and tolbutamide.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Identification of mutant Asp25 ...... nac, ibuprofen and tolbutamide
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921