Mammalian EGF receptor activation by the rhomboid protease RHBDL2 - Test2 - elhamkhani - TriplyDB

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

http://www.wikidata.org/entity/Q34178493

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Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis Large Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane Protease Structure and mechanism of rhomboid protease Coexpression and coregulation analysis of time-series gene expression data in estrogen-induced breast cancer cell RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.Differential evolution of members of the rhomboid gene family with conservative and divergent patterns.Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.The role of proteases in regulating Eph/ephrin signaling.Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics.iRhoms; Its Functions and Essential Roles.Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα Identification of signaling pathways modulated by RHBDD2 in breast cancer cells: a link to the unfolded protein response.Intramembrane proteolysis in regulated protein trafficking.Rhomboid proteases in plants - still in square one?The rhomboid protease family: a decade of progress on function and mechanism.Rhomboid proteins: a role in keratinocyte proliferation and cancer.Structural and mechanistic principles of intramembrane proteolysis--lessons from rhomboids.Bioinformatics perspective on rhomboid intramembrane protease evolution and function.Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4.Intramembrane proteases as drug targets.Age at menarche and age at natural menopause in East Asian women: a genome-wide association study.Roles of Grainyhead-like transcription factors in cancer.Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis.Regulation of receptor tyrosine kinase ligand processing Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.Rhomboid domain containing 1 inhibits cell apoptosis by upregulating AP-1 activity and its downstream target Bcl-3.RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer.Rhomboid family gene expression profiling in breast normal tissue and tumor samples.A Simple Cell-Based Assay for the Detection of Surface Protein Shedding by Rhomboid Proteases.Collagen-Induced Arthritis Analysis in Rhbdf2 Knockout Mouse.Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases.Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α converting enzyme.Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.RHBDL2 is a critical membrane protease for anoikis resistance in human malignant epithelial cells.

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P2860

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

http://www.wikidata.org/entity/Q34178493

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

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Mammalian EGF receptor activation by the rhomboid protease RHBDL2

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Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@nl

type

label

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@ast

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@en

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@nl

prefLabel

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@ast

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@en

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@nl

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Mammalian EGF receptor activation by the rhomboid protease RHBDL2

@en

P2093

Kvido Strisovsky

http://www.w3.org/2001/XMLSchema#string

Landian Hu

http://www.w3.org/2001/XMLSchema#string

Markus Zettl

http://www.w3.org/2001/XMLSchema#string

Matthew Freeman

http://www.w3.org/2001/XMLSchema#string

P2860

Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells

EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid

Epidermal growth factor-related peptides and their receptors in human malignancies

ADAMs: key components in EGFR signalling and development

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

Genome-scale loss-of-function screening with a lentiviral RNAi library.

Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases.

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421-427

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scholarly article

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10.1038/EMBOR.2011.50

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5

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12

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Marius K Lemberg

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2011-04-15T00:00:00Z

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51052379

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21494248

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3090019

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