Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
about
Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosaTylosis with oesophageal cancer: Diagnosis, management and molecular mechanismsNanoparticle-based targeted therapeutics in head-and-neck cancerTumor necrosis factor receptor 2: its contribution to acute cellular rejection and clear cell renal carcinomaPhosphatidylserine exposure is required for ADAM17 sheddase functionThe Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activityLarge Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseRhomboids, signalling and cell biologyCellular and molecular regulation of innate inflammatory responsesRegulation of tumour necrosis factor signalling: live or let dieIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysHaploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligasesRhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationA biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activationPlasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycleStructure and mechanism of rhomboid proteaseEctodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisRHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signalingiRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionActivated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSTrafficking of epidermal growth factor receptor ligands in polarized epithelial cells.iRhom2 is required for the secretion of mouse TNFαCytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking.Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structuresBio-Zombie: the rise of pseudoenzymes in biology.Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivoTACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.Proteomic analysis of differentially expressed skin proteins in iRhom2(Uncv) miceThe proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.Differential evolution of members of the rhomboid gene family with conservative and divergent patterns.iRhom2 mutation leads to aberrant hair follicle differentiation in mice.iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingiRhom1 regulates proteasome activity via PAC1/2 under ER stress
P2860
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P2860
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Tumor necrosis factor signalin ...... ficking and activation of TACE
@ast
Tumor necrosis factor signalin ...... ficking and activation of TACE
@en
Tumor necrosis factor signalin ...... ficking and activation of TACE
@nl
type
label
Tumor necrosis factor signalin ...... ficking and activation of TACE
@ast
Tumor necrosis factor signalin ...... ficking and activation of TACE
@en
Tumor necrosis factor signalin ...... ficking and activation of TACE
@nl
prefLabel
Tumor necrosis factor signalin ...... ficking and activation of TACE
@ast
Tumor necrosis factor signalin ...... ficking and activation of TACE
@en
Tumor necrosis factor signalin ...... ficking and activation of TACE
@nl
P2093
P2860
P356
P1433
P1476
Tumor necrosis factor signalin ...... ficking and activation of TACE
@en
P2093
Markus Zettl
Matthew Freeman
Neil Taylor
Yonka Christova
P2860
P304
P356
10.1126/SCIENCE.1214400
P407
P50
P577
2012-01-01T00:00:00Z